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Further studies on the interaction of the 5-hydroxytryptamine3 (5-HT3) receptor with arylpiperazine ligands. development of a new 5-HT3 receptor ligand showing potent acetylcholinesterase inhibitory properties.
Cappelli A, Gallelli A, Manini M, Anzini M, Mennuni L, Makovec F, Menziani MC, Alcaro S, Ortuso F, Vomero S. Cappelli A, et al. Among authors: anzini m. J Med Chem. 2005 May 19;48(10):3564-75. doi: 10.1021/jm0493461. J Med Chem. 2005. PMID: 15887964
Novel potent 5-HT(3) receptor ligands based on the pyrrolidone structure: synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities.
Cappelli A, Anzini M, Vomero S, Mennuni L, Makovec F, Doucet E, Hamon M, Menziani MC, De Benedetti PG, Giorgi G, Ghelardini C, Collina S. Cappelli A, et al. Among authors: anzini m. Bioorg Med Chem. 2002 Mar;10(3):779-801. doi: 10.1016/s0968-0896(01)00332-7. Bioorg Med Chem. 2002. PMID: 11814868
Synthesis, biological evaluation, and receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as kappa-opioid receptor agonists endowed with antinociceptive and antiamnesic activity.
Anzini M, Canullo L, Braile C, Cappelli A, Gallelli A, Vomero S, Menziani MC, De Benedetti PG, Rizzo M, Collina S, Azzolina O, Sbacchi M, Ghelardini C, Galeotti N. Anzini M, et al. J Med Chem. 2003 Aug 28;46(18):3853-64. doi: 10.1021/jm0307640. J Med Chem. 2003. PMID: 12930147
A non-peptide NK1 receptor agonist showing subpicomolar affinity.
Cappelli A, Giuliani G, Pericot Mohr Gl Gl, Gallelli A, Anzini M, Vomero S, Cupello A, Scarrone S, Matarrese M, Moresco RM, Fazio F, Finetti F, Morbidelli L, Ziche M. Cappelli A, et al. Among authors: anzini m. J Med Chem. 2004 Mar 11;47(6):1315-8. doi: 10.1021/jm034219a. J Med Chem. 2004. PMID: 14998319
Design, synthesis, structural studies, biological evaluation, and computational simulations of novel potent AT(1) angiotensin II receptor antagonists based on the 4-phenylquinoline structure.
Cappelli A, Pericot Mohr Gl Gl, Gallelli A, Rizzo M, Anzini M, Vomero S, Mennuni L, Ferrari F, Makovec F, Menziani MC, De Benedetti PG, Giorgi G. Cappelli A, et al. Among authors: anzini m. J Med Chem. 2004 May 6;47(10):2574-86. doi: 10.1021/jm031100t. J Med Chem. 2004. PMID: 15115399
102 results