Wong YN - Search Results

1

Enzyme kinetics for clinically relevant CYP inhibition.

Zhang ZY, Wong YN. Zhang ZY, et al. Among authors: wong yn. Curr Drug Metab. 2005 Jun;6(3):241-57. doi: 10.2174/1389200054021834. Curr Drug Metab. 2005. PMID: 15975042 Review.

2

In vitro interactions between a potential muscle relaxant E2101 and human cytochromes P450.

Zhang ZY, King BM, Mollova NN, Wong YN. Zhang ZY, et al. Among authors: wong yn. Drug Metab Dispos. 2002 Jul;30(7):805-13. doi: 10.1124/dmd.30.7.805. Drug Metab Dispos. 2002. PMID: 12065439

3

Preferential inducibility of CYP1A1 and CYP1A2 by TCDD: differential regulation in primary human hepatocytes versus transformed human cells.

Zhang ZY, Pelletier RD, Wong YN, Sugawara M, Zhao N, Littlefield BA. Zhang ZY, et al. Among authors: wong yn. Biochem Biophys Res Commun. 2006 Mar 10;341(2):399-407. doi: 10.1016/j.bbrc.2005.12.203. Epub 2006 Jan 11. Biochem Biophys Res Commun. 2006. PMID: 16426572

4

Pharmacokinetic characterization of a natural product-inspired novel MEK1 inhibitor E6201 in preclinical species.

Kumar V, Schuck EL, Pelletier RD, Farah N, Condon KB, Ye M, Rowbottom C, King BM, Zhang ZY, Saxton PL, Wong YN. Kumar V, et al. Among authors: wong yn. Cancer Chemother Pharmacol. 2012 Jan;69(1):229-37. doi: 10.1007/s00280-011-1687-8. Epub 2011 Jun 23. Cancer Chemother Pharmacol. 2012. PMID: 21698359

5

Quantitative liquid chromatography/mass spectrometry/mass spectrometry warfarin assay for in vitro cytochrome P450 studies.

Zhang ZY, King BM, Wong YN. Zhang ZY, et al. Among authors: wong yn. Anal Biochem. 2001 Nov 1;298(1):40-9. doi: 10.1006/abio.2001.5383. Anal Biochem. 2001. PMID: 11673893

6

Investigation of the metabolism of rufinamide and its interaction with valproate.

Williams ET, Carlson JE, Lai WG, Wong YN, Yoshimura T, Critchley DJ, Narurkar M. Williams ET, et al. Among authors: wong yn. Drug Metab Lett. 2011 Dec;5(4):280-9. doi: 10.2174/187231211798472511. Drug Metab Lett. 2011. PMID: 22022867

7

Application of a substrate cocktail approach in the assessment of cytochrome P450 induction using cultured human hepatocytes.

Pelletier RD, Lai WG, Wong YN. Pelletier RD, et al. Among authors: wong yn. J Biomol Screen. 2013 Feb;18(2):199-210. doi: 10.1177/1087057112463732. Epub 2012 Oct 15. J Biomol Screen. 2013. PMID: 23071008

8

Delineation of the interactions between the chemotherapeutic agent eribulin mesylate (E7389) and human CYP3A4.

Zhang ZY, King BM, Pelletier RD, Wong YN. Zhang ZY, et al. Among authors: wong yn. Cancer Chemother Pharmacol. 2008 Sep;62(4):707-16. doi: 10.1007/s00280-008-0755-1. Epub 2008 Apr 23. Cancer Chemother Pharmacol. 2008. PMID: 18431572

9

A Baeyer-Villiger oxidation specifically catalyzed by human flavin-containing monooxygenase 5.

Lai WG, Farah N, Moniz GA, Wong YN. Lai WG, et al. Among authors: wong yn. Drug Metab Dispos. 2011 Jan;39(1):61-70. doi: 10.1124/dmd.110.035360. Epub 2010 Oct 14. Drug Metab Dispos. 2011. PMID: 20947616

10

The conduct of in vitro studies to address time-dependent inhibition of drug-metabolizing enzymes: a perspective of the pharmaceutical research and manufacturers of America.

Grimm SW, Einolf HJ, Hall SD, He K, Lim HK, Ling KH, Lu C, Nomeir AA, Seibert E, Skordos KW, Tonn GR, Van Horn R, Wang RW, Wong YN, Yang TJ, Obach RS. Grimm SW, et al. Among authors: wong yn. Drug Metab Dispos. 2009 Jul;37(7):1355-70. doi: 10.1124/dmd.109.026716. Epub 2009 Apr 9. Drug Metab Dispos. 2009. PMID: 19359406

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