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Prospective gene expression analysis accurately subtypes acute leukaemia in children and establishes a commonality between hyperdiploidy and t(12;21) in acute lymphoblastic leukaemia.
van Delft FW, Bellotti T, Luo Z, Jones LK, Patel N, Yiannikouris O, Hill AS, Hubank M, Kempski H, Fletcher D, Chaplin T, Foot N, Young BD, Hann IM, Gammerman A, Saha V. van Delft FW, et al. Br J Haematol. 2005 Jul;130(1):26-35. doi: 10.1111/j.1365-2141.2005.05545.x. Br J Haematol. 2005. PMID: 15982341 Free article.
Complex genomic alterations and gene expression in acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21.
Strefford JC, van Delft FW, Robinson HM, Worley H, Yiannikouris O, Selzer R, Richmond T, Hann I, Bellotti T, Raghavan M, Young BD, Saha V, Harrison CJ. Strefford JC, et al. Among authors: van delft fw. Proc Natl Acad Sci U S A. 2006 May 23;103(21):8167-72. doi: 10.1073/pnas.0602360103. Epub 2006 May 15. Proc Natl Acad Sci U S A. 2006. PMID: 16702559 Free PMC article.
Genetic variegation of clonal architecture and propagating cells in leukaemia.
Anderson K, Lutz C, van Delft FW, Bateman CM, Guo Y, Colman SM, Kempski H, Moorman AV, Titley I, Swansbury J, Kearney L, Enver T, Greaves M. Anderson K, et al. Among authors: van delft fw. Nature. 2011 Jan 20;469(7330):356-61. doi: 10.1038/nature09650. Epub 2010 Dec 15. Nature. 2011. PMID: 21160474
Clonal origins of relapse in ETV6-RUNX1 acute lymphoblastic leukemia.
van Delft FW, Horsley S, Colman S, Anderson K, Bateman C, Kempski H, Zuna J, Eckert C, Saha V, Kearney L, Ford A, Greaves M. van Delft FW, et al. Blood. 2011 Jun 9;117(23):6247-54. doi: 10.1182/blood-2010-10-314674. Epub 2011 Apr 11. Blood. 2011. PMID: 21482711 Free article.
RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia.
Papaemmanuil E, Rapado I, Li Y, Potter NE, Wedge DC, Tubio J, Alexandrov LB, Van Loo P, Cooke SL, Marshall J, Martincorena I, Hinton J, Gundem G, van Delft FW, Nik-Zainal S, Jones DR, Ramakrishna M, Titley I, Stebbings L, Leroy C, Menzies A, Gamble J, Robinson B, Mudie L, Raine K, O'Meara S, Teague JW, Butler AP, Cazzaniga G, Biondi A, Zuna J, Kempski H, Muschen M, Ford AM, Stratton MR, Greaves M, Campbell PJ. Papaemmanuil E, et al. Among authors: van loo p, van delft fw. Nat Genet. 2014 Feb;46(2):116-25. doi: 10.1038/ng.2874. Epub 2014 Jan 12. Nat Genet. 2014. PMID: 24413735 Free PMC article.
Distinctive genotypes in infants with T-cell acute lymphoblastic leukaemia.
Mansur MB, van Delft FW, Colman SM, Furness CL, Gibson J, Emerenciano M, Kempski H, Clappier E, Cave H, Soulier J, Pombo-de-Oliveira MS, Greaves M, Ford AM. Mansur MB, et al. Among authors: van delft fw. Br J Haematol. 2015 Nov;171(4):574-84. doi: 10.1111/bjh.13613. Epub 2015 Jul 24. Br J Haematol. 2015. PMID: 26205622 Free PMC article.
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