Miller LR - Search Results

1

Ketoheterocycle-based inhibitors of cathepsin K: a novel entry into the synthesis of peptidic ketoheterocycles.

Tavares FX, Deaton DN, Miller AB, Miller LR, Wright LL. Tavares FX, et al. Among authors: miller lr, miller ab. Bioorg Med Chem Lett. 2005 Sep 1;15(17):3891-5. doi: 10.1016/j.bmcl.2005.05.091. Bioorg Med Chem Lett. 2005. PMID: 15993587

2

Exploration of the P1 SAR of aldehyde cathepsin K inhibitors.

Catalano JG, Deaton DN, Furfine ES, Hassell AM, McFadyen RB, Miller AB, Miller LR, Shewchuk LM, Willard DH Jr, Wright LL. Catalano JG, et al. Among authors: miller lr, miller ab. Bioorg Med Chem Lett. 2004 Jan 5;14(1):275-8. doi: 10.1016/j.bmcl.2003.09.088. Bioorg Med Chem Lett. 2004. PMID: 14684342

3

Design of potent, selective, and orally bioavailable inhibitors of cysteine protease cathepsin k.

Tavares FX, Boncek V, Deaton DN, Hassell AM, Long ST, Miller AB, Payne AA, Miller LR, Shewchuk LM, Wells-Knecht K, Willard DH Jr, Wright LL, Zhou HQ. Tavares FX, et al. Among authors: miller lr, miller ab. J Med Chem. 2004 Jan 29;47(3):588-99. doi: 10.1021/jm030373l. J Med Chem. 2004. PMID: 14736240

4

Design of small molecule ketoamide-based inhibitors of cathepsin K.

Catalano JG, Deaton DN, Long ST, McFadyen RB, Miller LR, Payne JA, Wells-Knecht KJ, Wright LL. Catalano JG, et al. Among authors: miller lr. Bioorg Med Chem Lett. 2004 Feb 9;14(3):719-22. doi: 10.1016/j.bmcl.2003.11.029. Bioorg Med Chem Lett. 2004. PMID: 14741275

5

Orally bioavailable small molecule ketoamide-based inhibitors of cathepsin K.

Barrett DG, Catalano JG, Deaton DN, Long ST, Miller LR, Tavares FX, Wells-Knecht KJ, Wright LL, Zhou HQ. Barrett DG, et al. Among authors: miller lr. Bioorg Med Chem Lett. 2004 May 17;14(10):2543-6. doi: 10.1016/j.bmcl.2004.02.085. Bioorg Med Chem Lett. 2004. PMID: 15109647

6

Exploration of the P2-P3 SAR of aldehyde cathepsin K inhibitors.

Boros EE, Deaton DN, Hassell AM, McFadyen RB, Miller AB, Miller LR, Paulick MG, Shewchuk LM, Thompson JB, Willard DH Jr, Wright LL. Boros EE, et al. Among authors: miller lr, miller ab. Bioorg Med Chem Lett. 2004 Jul 5;14(13):3425-9. doi: 10.1016/j.bmcl.2004.04.084. Bioorg Med Chem Lett. 2004. PMID: 15177446

7

Potent and selective P2-P3 ketoamide inhibitors of cathepsin K with good pharmacokinetic properties via favorable P1', P1, and/or P3 substitutions.

Barrett DG, Catalano JG, Deaton DN, Hassell AM, Long ST, Miller AB, Miller LR, Shewchuk LM, Wells-Knecht KJ, Willard DH Jr, Wright LL. Barrett DG, et al. Among authors: miller lr, miller ab. Bioorg Med Chem Lett. 2004 Oct 4;14(19):4897-902. doi: 10.1016/j.bmcl.2004.07.031. Bioorg Med Chem Lett. 2004. PMID: 15341947

8

Potent and selective ketoamide-based inhibitors of cysteine protease, cathepsin K.

Tavares FX, Deaton DN, Miller AB, Miller LR, Wright LL, Zhou HQ. Tavares FX, et al. Among authors: miller lr, miller ab. J Med Chem. 2004 Oct 7;47(21):5049-56. doi: 10.1021/jm0400799. J Med Chem. 2004. PMID: 15456248

9

Ketoamide-based inhibitors of cysteine protease, cathepsin K: P3 modifications.

Tavares FX, Deaton DN, Miller LR, Wright LL. Tavares FX, et al. Among authors: miller lr. J Med Chem. 2004 Oct 7;47(21):5057-68. doi: 10.1021/jm040107n. J Med Chem. 2004. PMID: 15456249

10

Novel and potent cyclic cyanamide-based cathepsin K inhibitors.

Deaton DN, Hassell AM, McFadyen RB, Miller AB, Miller LR, Shewchuk LM, Tavares FX, Willard DH Jr, Wright LL. Deaton DN, et al. Among authors: miller lr, miller ab. Bioorg Med Chem Lett. 2005 Apr 1;15(7):1815-9. doi: 10.1016/j.bmcl.2005.02.033. Bioorg Med Chem Lett. 2005. PMID: 15780613

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