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Substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonamides as antimitotics. Antiproliferative, antiangiogenic and antitumoral activity, and quantitative structure-activity relationships.
Fortin S, Wei L, Moreau E, Lacroix J, Côté MF, Petitclerc E, Kotra LP, Gaudreault RC. Fortin S, et al. Among authors: gaudreault rc. Eur J Med Chem. 2011 Nov;46(11):5327-42. doi: 10.1016/j.ejmech.2011.08.034. Epub 2011 Aug 30. Eur J Med Chem. 2011. PMID: 21920638
Imidazonaphthyridine systems (part 2): Functionalization of the phenyl ring linked to the pyridine pharmacophore and its replacement by a pyridinone ring produces intriguing differences in cytocidal activity.
Masurier N, Debiton E, Jacquemet A, Bussière A, Chezal JM, Ollivier A, Tétégan D, Andaloussi M, Galmier MJ, Lacroix J, Canitrot D, Teulade JC, Gaudreault RC, Chavignon O, Moreau E. Masurier N, et al. Among authors: gaudreault rc. Eur J Med Chem. 2012 Jun;52:137-50. doi: 10.1016/j.ejmech.2012.03.011. Epub 2012 Mar 20. Eur J Med Chem. 2012. PMID: 22503207
37 results