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Successful parallel development and integration of a plasmid-based biologic, container/closure system and electrokinetic delivery device.
Vaccine. 2006 May 22;24(21):4607-14. doi: 10.1016/j.vaccine.2005.08.049. Epub 2005 Aug 24.
Vaccine. 2006.
PMID: 16150516
Production of pharmaceutical-grade plasmids at high concentration and high supercoiled percentage.
Cai Y, Rodriguez S, Rameswaran R, Draghia-Akli R, Juba RJ Jr, Hebel H.
Cai Y, et al. Among authors: hebel h.
Vaccine. 2010 Feb 23;28(8):2046-52. doi: 10.1016/j.vaccine.2009.10.057. Epub 2009 Nov 5.
Vaccine. 2010.
PMID: 19896448
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DNA vaccine manufacture: scale and quality.
Cai Y, Rodriguez S, Hebel H.
Cai Y, et al. Among authors: hebel h.
Expert Rev Vaccines. 2009 Sep;8(9):1277-91. doi: 10.1586/erv.09.84.
Expert Rev Vaccines. 2009.
PMID: 19722898
Review.
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The significance of plasmid DNA preparations contaminated with bacterial genomic DNA on inflammatory responses following delivery of lipoplexes to the murine lung.
Bazzani RP, Cai Y, Hebel HL, Hyde SC, Gill DR.
Bazzani RP, et al. Among authors: hebel hl.
Biomaterials. 2011 Dec;32(36):9854-65. doi: 10.1016/j.biomaterials.2011.08.092. Epub 2011 Sep 23.
Biomaterials. 2011.
PMID: 21944469
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A novel mixing device for the reproducible generation of nonviral gene therapy formulations.
Davies LA, Nunez-Alonso GA, Hebel HL, Scheule RK, Cheng SH, Hyde SC, Gill DR.
Davies LA, et al. Among authors: hebel hl.
Biotechniques. 2010 Sep;49(3):666-8. doi: 10.2144/000113498.
Biotechniques. 2010.
PMID: 20854270
Free article.
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Intratumoral delivery of IL-12 gene by polyvinyl polymeric vector system to murine renal and colon carcinoma results in potent antitumor immunity.
Mendiratta SK, Quezada A, Matar M, Wang J, Hebel HL, Long S, Nordstrom JL, Pericle F.
Mendiratta SK, et al. Among authors: hebel hl.
Gene Ther. 1999 May;6(5):833-9. doi: 10.1038/sj.gt.3300891.
Gene Ther. 1999.
PMID: 10505108
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