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Crypt-restricted loss and decreased protein expression of cytochrome C oxidase subunit I as potential hypothesis-driven biomarkers of colon cancer risk.
Payne CM, Holubec H, Bernstein C, Bernstein H, Dvorak K, Green SB, Wilson M, Dall'Agnol M, Dvorakova B, Warneke J, Garewal H. Payne CM, et al. Among authors: holubec h. Cancer Epidemiol Biomarkers Prev. 2005 Sep;14(9):2066-75. doi: 10.1158/1055-9965.EPI-05-0180. Cancer Epidemiol Biomarkers Prev. 2005. PMID: 16172211
Deoxycholate, an endogenous tumor promoter and DNA damaging agent, modulates BRCA-1 expression in apoptosis-sensitive epithelial cells: loss of BRCA-1 expression in colonic adenocarcinomas.
Romagnolo DF, Chirnomas RB, Ku J, Jeffy BD, Payne CM, Holubec H, Ramsey L, Bernstein H, Bernstein C, Kunke K, Bhattacharyya A, Warneke J, Garewal H. Romagnolo DF, et al. Among authors: holubec h. Nutr Cancer. 2003;46(1):82-92. doi: 10.1207/S15327914NC4601_11. Nutr Cancer. 2003. PMID: 12925308
Reduced Pms2 expression in non-neoplastic flat mucosa from patients with colon cancer correlates with reduced apoptosis competence.
Bernstein H, Prasad A, Holubec H, Bernstein C, Payne CM, Ramsey L, Dvorakova K, Wilson M, Warneke JA, Garewal H. Bernstein H, et al. Among authors: holubec h. Appl Immunohistochem Mol Morphol. 2006 Jun;14(2):166-72. doi: 10.1097/01.pai.0000170533.61579.b9. Appl Immunohistochem Mol Morphol. 2006. PMID: 16785784 Clinical Trial.
Activation of the interleukin-6/STAT3 antiapoptotic pathway in esophageal cells by bile acids and low pH: relevance to barrett's esophagus.
Dvorak K, Chavarria M, Payne CM, Ramsey L, Crowley-Weber C, Dvorakova B, Dvorak B, Bernstein H, Holubec H, Sampliner RE, Bernstein C, Prasad A, Green SB, Garewal H. Dvorak K, et al. Among authors: holubec h. Clin Cancer Res. 2007 Sep 15;13(18 Pt 1):5305-13. doi: 10.1158/1078-0432.CCR-07-0483. Clin Cancer Res. 2007. PMID: 17875759
A proteomic study of resistance to deoxycholate-induced apoptosis.
Bernstein H, Payne CM, Kunke K, Crowley-Weber CL, Waltmire CN, Dvorakova K, Holubec H, Bernstein C, Vaillancourt RR, Raynes DA, Guerriero V, Garewal H. Bernstein H, et al. Among authors: holubec h. Carcinogenesis. 2004 May;25(5):681-92. doi: 10.1093/carcin/bgh072. Epub 2004 Jan 16. Carcinogenesis. 2004. PMID: 14729586
Unique dietary-related mouse model of colitis.
Bernstein H, Holubec H, Bernstein C, Ignatenko N, Gerner E, Dvorak K, Besselsen D, Ramsey L, Dall'Agnol M, Blohm-Mangone KA, Padilla-Torres J, Cui H, Garewal H, Payne CM. Bernstein H, et al. Among authors: holubec h. Inflamm Bowel Dis. 2006 Apr;12(4):278-93. doi: 10.1097/01.MIB.0000209789.14114.63. Inflamm Bowel Dis. 2006. PMID: 16633050
49 results