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A human beta-cell line for transplantation therapy to control type 1 diabetes.
Narushima M, Kobayashi N, Okitsu T, Tanaka Y, Li SA, Chen Y, Miki A, Tanaka K, Nakaji S, Takei K, Gutierrez AS, Rivas-Carrillo JD, Navarro-Alvarez N, Jun HS, Westerman KA, Noguchi H, Lakey JR, Leboulch P, Tanaka N, Yoon JW. Narushima M, et al. Among authors: okitsu t. Nat Biotechnol. 2005 Oct;23(10):1274-82. doi: 10.1038/nbt1145. Epub 2005 Sep 25. Nat Biotechnol. 2005. PMID: 16186810
Establishment of an immortalized human-liver endothelial cell line with SV40T and hTERT.
Matsumura T, Takesue M, Westerman KA, Okitsu T, Sakaguchi M, Fukazawa T, Totsugawa T, Noguchi H, Yamamoto S, Stolz DB, Tanaka N, Leboulch P, Kobayashi N. Matsumura T, et al. Among authors: okitsu t. Transplantation. 2004 May 15;77(9):1357-65. doi: 10.1097/01.tp.0000124286.82961.7e. Transplantation. 2004. PMID: 15167590
Reversal of mouse hepatic failure using an implanted liver-assist device containing ES cell-derived hepatocytes.
Soto-Gutiérrez A, Kobayashi N, Rivas-Carrillo JD, Navarro-Alvarez N, Zhao D, Okitsu T, Noguchi H, Basma H, Tabata Y, Chen Y, Tanaka K, Narushima M, Miki A, Ueda T, Jun HS, Yoon JW, Lebkowski J, Tanaka N, Fox IJ. Soto-Gutiérrez A, et al. Among authors: okitsu t. Nat Biotechnol. 2006 Nov;24(11):1412-9. doi: 10.1038/nbt1257. Epub 2006 Nov 5. Nat Biotechnol. 2006. PMID: 17086173 Free article.
Cell-permeable pentapeptide V5 inhibits apoptosis and enhances insulin secretion, allowing experimental single-donor islet transplantation in mice.
Rivas-Carrillo JD, Soto-Gutierrez A, Navarro-Alvarez N, Noguchi H, Okitsu T, Chen Y, Yuasa T, Tanaka K, Narushima M, Miki A, Misawa H, Tabata Y, Jun HS, Matsumoto S, Fox IJ, Tanaka N, Kobayashi N. Rivas-Carrillo JD, et al. Among authors: okitsu t. Diabetes. 2007 May;56(5):1259-67. doi: 10.2337/db06-1679. Epub 2007 Feb 7. Diabetes. 2007. PMID: 17287463
Survival of liver failure pigs by transplantation of reversibly immortalized human hepatocytes with Tamoxifen-mediated self-recombination.
Totsugawa T, Yong C, Rivas-Carrillo JD, Soto-Gutierrez A, Navarro-Alvarez N, Noguchi H, Okitsu T, Westerman KA, Kohara M, Reth M, Tanaka N, Leboulch P, Kobayashi N. Totsugawa T, et al. Among authors: okitsu t. J Hepatol. 2007 Jul;47(1):74-82. doi: 10.1016/j.jhep.2007.02.019. Epub 2007 Mar 15. J Hepatol. 2007. PMID: 17434229
Current cell-based approaches for the treatment of diabetes mellitus.
Rivas-Carrillo JD, Okitsu T, Kobayashi N. Rivas-Carrillo JD, et al. Among authors: okitsu t. Biotechnol Genet Eng Rev. 2007;24:281-95. doi: 10.1080/02648725.2007.10648104. Biotechnol Genet Eng Rev. 2007. PMID: 18059638 Review. No abstract available.
231 results