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Pioglitazone decreases carotid intima-media thickness independently of glycemic control in patients with type 2 diabetes mellitus: results from a controlled randomized study.
Langenfeld MR, Forst T, Hohberg C, Kann P, Lübben G, Konrad T, Füllert SD, Sachara C, Pfützner A. Langenfeld MR, et al. Among authors: sachara c. Circulation. 2005 May 17;111(19):2525-31. doi: 10.1161/01.CIR.0000165072.01672.21. Epub 2005 May 9. Circulation. 2005. PMID: 15883215 Clinical Trial.
Pharmacological PPARgamma stimulation in contrast to beta cell stimulation results in an improvement in adiponectin and proinsulin intact levels and reduces intima media thickness in patients with type 2 diabetes.
Forst T, Hohberg C, Fuellert SD, Lübben G, Konrad T, Löbig M, Weber MM, Sachara C, Gottschall V, Pfützner A. Forst T, et al. Among authors: sachara c. Horm Metab Res. 2005 Aug;37(8):521-7. doi: 10.1055/s-2005-870322. Horm Metab Res. 2005. PMID: 16138267 Clinical Trial.