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Transforming growth factor-beta signaling mediates hypoxia-induced pulmonary arterial remodeling and inhibition of alveolar development in newborn mouse lung.
Ambalavanan N, Nicola T, Hagood J, Bulger A, Serra R, Murphy-Ullrich J, Oparil S, Chen YF. Ambalavanan N, et al. Among authors: chen yf. Am J Physiol Lung Cell Mol Physiol. 2008 Jul;295(1):L86-95. doi: 10.1152/ajplung.00534.2007. Epub 2008 May 16. Am J Physiol Lung Cell Mol Physiol. 2008. PMID: 18487357 Free PMC article.
Inhibition of transforming growth factor-beta signaling induces left ventricular dilation and dysfunction in the pressure-overloaded heart.
Lucas JA, Zhang Y, Li P, Gong K, Miller AP, Hassan E, Hage F, Xing D, Wells B, Oparil S, Chen YF. Lucas JA, et al. Among authors: chen yf. Am J Physiol Heart Circ Physiol. 2010 Feb;298(2):H424-32. doi: 10.1152/ajpheart.00529.2009. Epub 2009 Nov 20. Am J Physiol Heart Circ Physiol. 2010. PMID: 19933419 Free PMC article.
Hypoxia-induced inhibition of lung development is attenuated by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone.
Nicola T, Ambalavanan N, Zhang W, James ML, Rehan V, Halloran B, Olave N, Bulger A, Oparil S, Chen YF. Nicola T, et al. Among authors: chen yf. Am J Physiol Lung Cell Mol Physiol. 2011 Jul;301(1):L125-34. doi: 10.1152/ajplung.00074.2011. Epub 2011 Apr 29. Am J Physiol Lung Cell Mol Physiol. 2011. PMID: 21531777 Free PMC article.
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