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Administration of Lispro insulin with meals improves glycemic control, increases circulating leptin, and suppresses ghrelin, compared with regular/NPH insulin in female patients with type 1 diabetes.
Griffen SC, Oostema K, Stanhope KL, Graham J, Styne DM, Glaser N, Cummings DE, Connors MH, Havel PJ. Griffen SC, et al. Among authors: graham j. J Clin Endocrinol Metab. 2006 Feb;91(2):485-91. doi: 10.1210/jc.2005-1338. Epub 2005 Nov 29. J Clin Endocrinol Metab. 2006. PMID: 16317063 Clinical Trial.
Hepatic Src homology phosphatase 2 regulates energy balance in mice.
Nagata N, Matsuo K, Bettaieb A, Bakke J, Matsuo I, Graham J, Xi Y, Liu S, Tomilov A, Tomilova N, Gray S, Jung DY, Ramsey JJ, Kim JK, Cortopassi G, Havel PJ, Haj FG. Nagata N, et al. Among authors: graham j. Endocrinology. 2012 Jul;153(7):3158-69. doi: 10.1210/en.2012-1406. Epub 2012 May 22. Endocrinology. 2012. PMID: 22619361 Free PMC article.
Protein tyrosine phosphatase 1B regulates pyruvate kinase M2 tyrosine phosphorylation.
Bettaieb A, Bakke J, Nagata N, Matsuo K, Xi Y, Liu S, AbouBechara D, Melhem R, Stanhope K, Cummings B, Graham J, Bremer A, Zhang S, Lyssiotis CA, Zhang ZY, Cantley LC, Havel PJ, Haj FG. Bettaieb A, et al. Among authors: graham j. J Biol Chem. 2013 Jun 14;288(24):17360-71. doi: 10.1074/jbc.M112.441469. Epub 2013 May 2. J Biol Chem. 2013. PMID: 23640882 Free PMC article.
Ileal interposition surgery targets the hepatic TGF-β pathway, influencing gluconeogenesis and mitochondrial bioenergetics in the UCD-T2DM rat model of diabetes.
Hung C, Napoli E, Ross-Inta C, Graham J, Flores-Torres AL, Stanhope KL, Froment P, Havel PJ, Giulivi C. Hung C, et al. Among authors: graham j. FASEB J. 2019 Oct;33(10):11270-11283. doi: 10.1096/fj.201802714R. Epub 2019 Jul 15. FASEB J. 2019. PMID: 31307210 Free PMC article.
This study demonstrates for the first time the presence of metabolic pathways that complement the effects of IT surgery to maximize its benefits and potentially identify similarly effective, durable, and less invasive therapeutic options for metabolic disease, including inhibitor …
This study demonstrates for the first time the presence of metabolic pathways that complement the effects of IT surgery to maximize its bene …
5,261 results