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Page 1
CCR2 modulates inflammatory and metabolic effects of high-fat feeding.
Weisberg SP, Hunter D, Huber R, Lemieux J, Slaymaker S, Vaddi K, Charo I, Leibel RL, Ferrante AW Jr. Weisberg SP, et al. Among authors: huber r. J Clin Invest. 2006 Jan;116(1):115-24. doi: 10.1172/JCI24335. Epub 2005 Dec 8. J Clin Invest. 2006. PMID: 16341265 Free PMC article.
Discovery and pharmacological characterization of a novel rodent-active CCR2 antagonist, INCB3344.
Brodmerkel CM, Huber R, Covington M, Diamond S, Hall L, Collins R, Leffet L, Gallagher K, Feldman P, Collier P, Stow M, Gu X, Baribaud F, Shin N, Thomas B, Burn T, Hollis G, Yeleswaram S, Solomon K, Friedman S, Wang A, Xue CB, Newton RC, Scherle P, Vaddi K. Brodmerkel CM, et al. Among authors: huber r. J Immunol. 2005 Oct 15;175(8):5370-8. doi: 10.4049/jimmunol.175.8.5370. J Immunol. 2005. PMID: 16210643
Discovery of 1'-(1-phenylcyclopropane-carbonyl)-3H-spiro[isobenzofuran-1,3'-pyrrolidin]-3-one as a novel steroid mimetic scaffold for the potent and tissue-specific inhibition of 11β-HSD1 using a scaffold-hopping approach.
Zhang C, Xu M, He C, Zhuo J, Burns DM, Qian DQ, Lin Q, Li YL, Chen L, Shi E, Agrios C, Weng L, Sharief V, Jalluri R, Li Y, Scherle P, Diamond S, Hunter D, Covington M, Marando C, Wynn R, Katiyar K, Contel N, Vaddi K, Yeleswaram S, Hollis G, Huber R, Friedman S, Metcalf B, Yao W. Zhang C, et al. Among authors: huber r. Bioorg Med Chem Lett. 2022 Aug 1;69:128782. doi: 10.1016/j.bmcl.2022.128782. Epub 2022 May 7. Bioorg Med Chem Lett. 2022. PMID: 35537608
INCB040093 Is a Novel PI3Kδ Inhibitor for the Treatment of B Cell Lymphoid Malignancies.
Shin N, Li YL, Mei S, Wang KH, Hall L, Katiyar K, Wang Q, Yang G, Rumberger B, Leffet L, He X, Rupar M, Bowman K, Favata M, Li J, Liu M, Li Y, Covington M, Koblish H, Soloviev M, Shuey D, Burn T, Diamond S, Fridman J, Combs A, Yao W, Yeleswaram S, Hollis G, Vaddi K, Huber R, Newton R, Scherle P. Shin N, et al. Among authors: huber r. J Pharmacol Exp Ther. 2018 Jan;364(1):120-130. doi: 10.1124/jpet.117.244947. Epub 2017 Nov 10. J Pharmacol Exp Ther. 2018. PMID: 29127109
Preclinical characterization of INCB053914, a novel pan-PIM kinase inhibitor, alone and in combination with anticancer agents, in models of hematologic malignancies.
Koblish H, Li YL, Shin N, Hall L, Wang Q, Wang K, Covington M, Marando C, Bowman K, Boer J, Burke K, Wynn R, Margulis A, Reuther GW, Lambert QT, Dostalik Roman V, Zhang K, Feng H, Xue CB, Diamond S, Hollis G, Yeleswaram S, Yao W, Huber R, Vaddi K, Scherle P. Koblish H, et al. Among authors: huber r. PLoS One. 2018 Jun 21;13(6):e0199108. doi: 10.1371/journal.pone.0199108. eCollection 2018. PLoS One. 2018. PMID: 29927999 Free PMC article.
The 11-beta-hydroxysteroid dehydrogenase type 1 inhibitor INCB13739 improves hyperglycemia in patients with type 2 diabetes inadequately controlled by metformin monotherapy.
Rosenstock J, Banarer S, Fonseca VA, Inzucchi SE, Sun W, Yao W, Hollis G, Flores R, Levy R, Williams WV, Seckl JR, Huber R; INCB13739-202 Principal Investigators. Rosenstock J, et al. Among authors: huber r. Diabetes Care. 2010 Jul;33(7):1516-22. doi: 10.2337/dc09-2315. Epub 2010 Apr 22. Diabetes Care. 2010. PMID: 20413513 Free PMC article. Clinical Trial.
Large area robotically assisted optical coherence tomography (LARA-OCT).
Lotz S, Göb M, Böttger S, Ha-Wissel L, Hundt J, Ernst F, Huber R. Lotz S, et al. Among authors: huber r. Biomed Opt Express. 2024 May 30;15(6):3993-4009. doi: 10.1364/BOE.525524. eCollection 2024 Jun 1. Biomed Opt Express. 2024. PMID: 38867778 Free PMC article.
Harmonic Imaging of Stem Cells in Whole Blood at GHz Pixel Rate.
Karpf S, Glöckner Burmeister N, Dubreil L, Ghosh S, Hollandi R, Pichon J, Leroux I, Henkel A, Lutz V, Jurkevičius J, Latshaw A, Kilin V, Kutscher T, Wiggert M, Saavedra-Villanueva O, Vogel A, Huber RA, Horvath P, Rouger K, Bonacina L. Karpf S, et al. Among authors: huber ra. Small. 2024 Jun 11:e2401472. doi: 10.1002/smll.202401472. Online ahead of print. Small. 2024. PMID: 38863131
Transparency and Reproducibility in the Adolescent Brain Cognitive Development (ABCD) Study.
Lopez DA, Cardenas-Iniguez C, Subramaniam P, Adise S, Bottenhorn KL, Badilla P, Mukwekwerere E, Tally L, Ahanmisi O, Bedichek IL, Matera SD, Perez-Tamayo GM, Sissons N, Winters O, Harkness A, Nakiyingi E, Encizo J, Xiang Z, Wilson IG, Smith AN, Hill AR, Adames AK, Robertson E, Boughter JR, Lopez-Flores A, Skoler ER, Dorholt L, Nagel BJ, Huber RS. Lopez DA, et al. Among authors: huber rs. medRxiv [Preprint]. 2024 May 31:2024.05.30.24308222. doi: 10.1101/2024.05.30.24308222. medRxiv. 2024. PMID: 38854118 Free PMC article. Preprint.
2,400 results