Linton GF - Search Results

1

Correction of canine X-linked severe combined immunodeficiency by in vivo retroviral gene therapy.

Ting-De Ravin SS, Kennedy DR, Naumann N, Kennedy JS, Choi U, Hartnett BJ, Linton GF, Whiting-Theobald NL, Moore PF, Vernau W, Malech HL, Felsburg PJ. Ting-De Ravin SS, et al. Among authors: linton gf. Blood. 2006 Apr 15;107(8):3091-7. doi: 10.1182/blood-2005-10-4057. Epub 2005 Dec 29. Blood. 2006. PMID: 16384923 Free PMC article.

2

Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils.

Kang EM, Choi U, Theobald N, Linton G, Long Priel DA, Kuhns D, Malech HL. Kang EM, et al. Blood. 2010 Jan 28;115(4):783-91. doi: 10.1182/blood-2009-05-222760. Epub 2009 Dec 1. Blood. 2010. PMID: 19965657 Free PMC article. Clinical Trial.

3

Concentrated RD114-pseudotyped MFGS-gp91phox vector achieves high levels of functional correction of the chronic granulomatous disease oxidase defect in NOD/SCID/beta -microglobulin-/- repopulating mobilized human peripheral blood CD34+ cells.

Brenner S, Whiting-Theobald NL, Linton GF, Holmes KL, Anderson-Cohen M, Kelly PF, Vanin EF, Pilon AM, Bodine DM, Horwitz ME, Malech HL. Brenner S, et al. Among authors: linton gf. Blood. 2003 Oct 15;102(8):2789-97. doi: 10.1182/blood-2002-05-1482. Epub 2003 Jun 26. Blood. 2003. PMID: 12829597 Free article.

4

WHIM syndrome myelokathexis reproduced in the NOD/SCID mouse xenotransplant model engrafted with healthy human stem cells transduced with C-terminus-truncated CXCR4.

Kawai T, Choi U, Cardwell L, DeRavin SS, Naumann N, Whiting-Theobald NL, Linton GF, Moon J, Murphy PM, Malech HL. Kawai T, et al. Among authors: linton gf. Blood. 2007 Jan 1;109(1):78-84. doi: 10.1182/blood-2006-05-025296. Epub 2006 Aug 31. Blood. 2007. PMID: 16946301 Free PMC article.

5

Gene therapy improves immune function in preadolescents with X-linked severe combined immunodeficiency.

Chinen J, Davis J, De Ravin SS, Hay BN, Hsu AP, Linton GF, Naumann N, Nomicos EY, Silvin C, Ulrick J, Whiting-Theobald NL, Malech HL, Puck JM. Chinen J, et al. Among authors: linton gf. Blood. 2007 Jul 1;110(1):67-73. doi: 10.1182/blood-2006-11-058933. Epub 2007 Mar 16. Blood. 2007. PMID: 17369490 Free PMC article. Clinical Trial.

6

The late dividing population of gamma-retroviral vector transduced human mobilized peripheral blood progenitor cells contributes most to gene-marked cell engraftment in nonobese diabetic/severe combined immunodeficient mice.

Brenner S, Ryser MF, Whiting-Theobald NL, Gentsch M, Linton GF, Malech HL. Brenner S, et al. Among authors: linton gf. Stem Cells. 2007 Jul;25(7):1807-13. doi: 10.1634/stemcells.2006-0581. Epub 2007 Apr 26. Stem Cells. 2007. PMID: 17464090

7

Diprotin A infusion into nonobese diabetic/severe combined immunodeficiency mice markedly enhances engraftment of human mobilized CD34+ peripheral blood cells.

Kawai T, Choi U, Liu PC, Whiting-Theobald NL, Linton GF, Malech HL. Kawai T, et al. Among authors: linton gf. Stem Cells Dev. 2007 Jun;16(3):361-70. doi: 10.1089/scd.2007.9997. Stem Cells Dev. 2007. PMID: 17610366

8

CD34+ peripheral blood progenitors as a target for genetic correction of the two flavocytochrome b558 defective forms of chronic granulomatous disease.

Li F, Linton GF, Sekhsaria S, Whiting-Theobald N, Katkin JP, Gallin JI, Malech HL. Li F, et al. Among authors: linton gf. Blood. 1994 Jul 1;84(1):53-8. Blood. 1994. PMID: 7517218 Free article.

9

A bicistronic retrovirus vector containing a picornavirus internal ribosome entry site allows for correction of X-linked CGD by selection for MDR1 expression.

Sokolic RA, Sekhsaria S, Sugimoto Y, Whiting-Theobald N, Linton GF, Li F, Gottesman MM, Malech HL. Sokolic RA, et al. Among authors: linton gf. Blood. 1996 Jan 1;87(1):42-50. Blood. 1996. PMID: 8547675 Free article.

10

Genetic correction of p67phox deficient chronic granulomatous disease using peripheral blood progenitor cells as a target for retrovirus mediated gene transfer.

Weil WM, Linton GF, Whiting-Theobald N, Vowells SJ, Rafferty SP, Li F, Malech HL. Weil WM, et al. Among authors: linton gf. Blood. 1997 Mar 1;89(5):1754-61. Blood. 1997. PMID: 9057660 Free article.

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