Uehara A - Search Results

1

Promoter hypomethylation of Toll-like receptor-2 gene is associated with increased proinflammatory response toward bacterial peptidoglycan in cystic fibrosis bronchial epithelial cells.

Shuto T, Furuta T, Oba M, Xu H, Li JD, Cheung J, Gruenert DC, Uehara A, Suico MA, Okiyoneda T, Kai H. Shuto T, et al. Among authors: uehara a. FASEB J. 2006 Apr;20(6):782-4. doi: 10.1096/fj.05-4934fje. Epub 2006 Feb 14. FASEB J. 2006. PMID: 16478769

2

Chemically synthesized pathogen-associated molecular patterns increase the expression of peptidoglycan recognition proteins via toll-like receptors, NOD1 and NOD2 in human oral epithelial cells.

Uehara A, Sugawara Y, Kurata S, Fujimoto Y, Fukase K, Kusumoto S, Satta Y, Sasano T, Sugawara S, Takada H. Uehara A, et al. Cell Microbiol. 2005 May;7(5):675-86. doi: 10.1111/j.1462-5822.2004.00500.x. Cell Microbiol. 2005. PMID: 15839897

3

Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines.

Uehara A, Fujimoto Y, Fukase K, Takada H. Uehara A, et al. Mol Immunol. 2007 May;44(12):3100-11. doi: 10.1016/j.molimm.2007.02.007. Epub 2007 Apr 2. Mol Immunol. 2007. PMID: 17403538

4

Toll-like receptors, NOD1, and NOD2 in oral epithelial cells.

Sugawara Y, Uehara A, Fujimoto Y, Kusumoto S, Fukase K, Shibata K, Sugawara S, Sasano T, Takada H. Sugawara Y, et al. Among authors: uehara a. J Dent Res. 2006 Jun;85(6):524-9. doi: 10.1177/154405910608500609. J Dent Res. 2006. PMID: 16723649

5

Dual regulation of interleukin-8 production in human oral epithelial cells upon stimulation with gingipains from Porphyromonas gingivalis.

Uehara A, Naito M, Imamura T, Potempa J, Travis J, Nakayama K, Takada H. Uehara A, et al. J Med Microbiol. 2008 Apr;57(Pt 4):500-507. doi: 10.1099/jmm.0.47679-0. J Med Microbiol. 2008. PMID: 18349372

6

A polymer-type water-soluble peptidoglycan exhibited both Toll-like receptor 2- and NOD2-agonistic activities, resulting in synergistic activation of human monocytic cells.

Natsuka M, Uehara A, Yang S, Echigo S, Takada H. Natsuka M, et al. Among authors: uehara a. Innate Immun. 2008 Oct;14(5):298-308. doi: 10.1177/1753425908096518. Innate Immun. 2008. PMID: 18809654 Free article.

7

Proinflammatory cytokines induce proteinase 3 as membrane-bound and secretory forms in human oral epithelial cells and antibodies to proteinase 3 activate the cells through protease-activated receptor-2.

Uehara A, Sugawara Y, Sasano T, Takada H, Sugawara S. Uehara A, et al. J Immunol. 2004 Sep 15;173(6):4179-89. doi: 10.4049/jimmunol.173.6.4179. J Immunol. 2004. PMID: 15356169 Retracted.

8

Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2- and NOD1-dependent manner, respectively, in human monocytic cells in culture.

Uehara A, Yang S, Fujimoto Y, Fukase K, Kusumoto S, Shibata K, Sugawara S, Takada H. Uehara A, et al. Cell Microbiol. 2005 Jan;7(1):53-61. doi: 10.1111/j.1462-5822.2004.00433.x. Cell Microbiol. 2005. PMID: 15617523

9

Antibodies to proteinase 3 prime human monocytic cells via protease-activated receptor-2 and NF-kappaB for Toll-like receptor- and NOD-dependent activation.

Uehara A, Iwashiro A, Sato T, Yokota S, Takada H. Uehara A, et al. Mol Immunol. 2007 Jul;44(14):3552-62. doi: 10.1016/j.molimm.2007.03.010. Epub 2007 Apr 23. Mol Immunol. 2007. PMID: 17452051

10

Meso-diaminopimelic acid and meso-lanthionine, amino acids specific to bacterial peptidoglycans, activate human epithelial cells through NOD1.

Uehara A, Fujimoto Y, Kawasaki A, Kusumoto S, Fukase K, Takada H. Uehara A, et al. J Immunol. 2006 Aug 1;177(3):1796-804. doi: 10.4049/jimmunol.177.3.1796. J Immunol. 2006. PMID: 16849490

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