MacLean D - Search Results

1

Allosteric activation of the follicle-stimulating hormone (FSH) receptor by selective, nonpeptide agonists.

Yanofsky SD, Shen ES, Holden F, Whitehorn E, Aguilar B, Tate E, Holmes CP, Scheuerman R, MacLean D, Wu MM, Frail DE, López FJ, Winneker R, Arey BJ, Barrett RW. Yanofsky SD, et al. Among authors: maclean d. J Biol Chem. 2006 May 12;281(19):13226-13233. doi: 10.1074/jbc.M600601200. Epub 2006 Mar 15. J Biol Chem. 2006. PMID: 16540466 Free article.

2

Agonists of the follicle stimulating hormone receptor from an encoded thiazolidinone library.

Maclean D, Holden F, Davis AM, Scheuerman RA, Yanofsky S, Holmes CP, Fitch WL, Tsutsui K, Barrett RW, Gallop MA. Maclean D, et al. J Comb Chem. 2004 Mar-Apr;6(2):196-206. doi: 10.1021/cc0300154. J Comb Chem. 2004. PMID: 15002967

3

Versatile approach to encoding combinatorial organic syntheses using chemically robust secondary amine tags.

Ni ZJ, Maclean D, Holmes CP, Murphy MM, Ruhland B, Jacobs JW, Gordon EM, Gallop MA. Ni ZJ, et al. Among authors: maclean d. J Med Chem. 1996 Apr 12;39(8):1601-8. doi: 10.1021/jm960043j. J Med Chem. 1996. PMID: 8648599

4

Encoded combinatorial chemistry: binary coding using chemically robust secondary amine tags.

Ni ZJ, Maclean D, Holmes CP, Gallop MA. Ni ZJ, et al. Among authors: maclean d. Methods Enzymol. 1996;267:261-72. doi: 10.1016/s0076-6879(96)67018-9. Methods Enzymol. 1996. PMID: 8743322 No abstract available.

5

Glossary of terms used in combinatorial chemistry (technical report).

Maclean D, Baldwin JJ, Ivanov VT, Kato Y, Shaw A, Schenider P, Gordon EM. Maclean D, et al. J Comb Chem. 2000 Nov-Dec;2(6):562-78. doi: 10.1021/cc000071u. J Comb Chem. 2000. PMID: 11126286 No abstract available.

6

The reversed Kenner linker: a new safety-catch linker for the preparation of N-alkyl sulfonamides.

Maclean D, Hale R, Chen M. Maclean D, et al. Org Lett. 2001 Sep 20;3(19):2977-80. doi: 10.1021/ol0163124. Org Lett. 2001. PMID: 11554822

7

Screening for novel antimicrobials from encoded combinatorial libraries by using a two-dimensional agar format.

Silen JL, Lu AT, Solas DW, Gore MA, MacLean D, Shah NH, Coffin JM, Bhinderwala NS, Wang Y, Tsutsui KT, Look GC, Campbell DA, Hale RL, Navre M, DeLuca-Flaherty CR. Silen JL, et al. Among authors: maclean d. Antimicrob Agents Chemother. 1998 Jun;42(6):1447-53. doi: 10.1128/AAC.42.6.1447. Antimicrob Agents Chemother. 1998. PMID: 9624492 Free PMC article.

8

Critical Cysteine Residues in Both the Calcium-Sensing Receptor and the Allosteric Activator AMG 416 Underlie the Mechanism of Action.

Alexander ST, Hunter T, Walter S, Dong J, Maclean D, Baruch A, Subramanian R, Tomlinson JE. Alexander ST, et al. Among authors: maclean d. Mol Pharmacol. 2015 Nov;88(5):853-65. doi: 10.1124/mol.115.098392. Epub 2015 Aug 19. Mol Pharmacol. 2015. PMID: 26290606

9

Encoded combinatorial chemistry: synthesis and screening of a library of highly functionalized pyrrolidines.

Maclean D, Schullek JR, Murphy MM, Ni ZJ, Gordon EM, Gallop MA. Maclean D, et al. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):2805-10. doi: 10.1073/pnas.94.7.2805. Proc Natl Acad Sci U S A. 1997. PMID: 9096301 Free PMC article.

10

Combinatorial modification of natural products: preparation of unencoded and encoded libraries of Rauwolfia alkaloids.

Atuegbu A, Maclean D, Nguyen C, Gordon EM, Jacobs JW. Atuegbu A, et al. Among authors: maclean d. Bioorg Med Chem. 1996 Jul;4(7):1097-106. doi: 10.1016/0968-0896(96)00093-4. Bioorg Med Chem. 1996. PMID: 8831981

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