Evans RM - Search Results

1

A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway.

Zhou J, Zhai Y, Mu Y, Gong H, Uppal H, Toma D, Ren S, Evans RM, Xie W. Zhou J, et al. Among authors: evans rm. J Biol Chem. 2006 May 26;281(21):15013-20. doi: 10.1074/jbc.M511116200. Epub 2006 Mar 23. J Biol Chem. 2006. PMID: 16556603 Free PMC article.

2

Humanized xenobiotic response in mice expressing nuclear receptor SXR.

Xie W, Barwick JL, Downes M, Blumberg B, Simon CM, Nelson MC, Neuschwander-Tetri BA, Brunt EM, Guzelian PS, Evans RM. Xie W, et al. Among authors: evans rm. Nature. 2000 Jul 27;406(6794):435-9. doi: 10.1038/35019116. Nature. 2000. PMID: 10935643

3

Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR.

Xie W, Barwick JL, Simon CM, Pierce AM, Safe S, Blumberg B, Guzelian PS, Evans RM. Xie W, et al. Among authors: evans rm. Genes Dev. 2000 Dec 1;14(23):3014-23. doi: 10.1101/gad.846800. Genes Dev. 2000. PMID: 11114890 Free PMC article.

4

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

Xie W, Radominska-Pandya A, Shi Y, Simon CM, Nelson MC, Ong ES, Waxman DJ, Evans RM. Xie W, et al. Among authors: evans rm. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3375-80. doi: 10.1073/pnas.051014398. Proc Natl Acad Sci U S A. 2001. PMID: 11248086 Free PMC article.

5

Orphan nuclear receptors: the exotics of xenobiotics.

Xie W, Evans RM. Xie W, et al. Among authors: evans rm. J Biol Chem. 2001 Oct 12;276(41):37739-42. doi: 10.1074/jbc.R100033200. Epub 2001 Jul 17. J Biol Chem. 2001. PMID: 11459851 Free article. Review. No abstract available.

6

Pharmaceutical use of mouse models humanized for the xenobiotic receptor.

Xie W, Evans RM. Xie W, et al. Among authors: evans rm. Drug Discov Today. 2002 May 1;7(9):509-15. doi: 10.1016/s1359-6446(02)02251-1. Drug Discov Today. 2002. PMID: 11983567 Review.

7

Vitamin D receptor as an intestinal bile acid sensor.

Makishima M, Lu TT, Xie W, Whitfield GK, Domoto H, Evans RM, Haussler MR, Mangelsdorf DJ. Makishima M, et al. Among authors: evans rm. Science. 2002 May 17;296(5571):1313-6. doi: 10.1126/science.1070477. Science. 2002. PMID: 12016314

8

Regulation of a xenobiotic sulfonation cascade by nuclear pregnane X receptor (PXR).

Sonoda J, Xie W, Rosenfeld JM, Barwick JL, Guzelian PS, Evans RM. Sonoda J, et al. Among authors: evans rm. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13801-6. doi: 10.1073/pnas.212494599. Epub 2002 Oct 7. Proc Natl Acad Sci U S A. 2002. PMID: 12370413 Free PMC article.

9

A nuclear receptor-mediated xenobiotic response and its implication in drug metabolism and host protection.

Sonoda J, Rosenfeld JM, Xu L, Evans RM, Xie W. Sonoda J, et al. Among authors: evans rm. Curr Drug Metab. 2003 Feb;4(1):59-72. doi: 10.2174/1389200033336739. Curr Drug Metab. 2003. PMID: 12570746 Review.

10

Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor.

Xie W, Yeuh MF, Radominska-Pandya A, Saini SP, Negishi Y, Bottroff BS, Cabrera GY, Tukey RH, Evans RM. Xie W, et al. Among authors: evans rm. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4150-5. doi: 10.1073/pnas.0438010100. Epub 2003 Mar 18. Proc Natl Acad Sci U S A. 2003. PMID: 12644700 Free PMC article.

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