Sun S - Search Results

1

CpG-induced tyrosine phosphorylation occurs via a TLR9-independent mechanism and is required for cytokine secretion.

Sanjuan MA, Rao N, Lai KT, Gu Y, Sun S, Fuchs A, Fung-Leung WP, Colonna M, Karlsson L. Sanjuan MA, et al. Among authors: sun s. J Cell Biol. 2006 Mar 27;172(7):1057-68. doi: 10.1083/jcb.200508058. J Cell Biol. 2006. PMID: 16567503 Free PMC article.

2

Identification of a potent and selective noncovalent cathepsin S inhibitor.

Thurmond RL, Sun S, Sehon CA, Baker SM, Cai H, Gu Y, Jiang W, Riley JP, Williams KN, Edwards JP, Karlsson L. Thurmond RL, et al. Among authors: sun s. J Pharmacol Exp Ther. 2004 Jan;308(1):268-76. doi: 10.1124/jpet.103.056879. Epub 2003 Oct 17. J Pharmacol Exp Ther. 2004. PMID: 14566006

3

A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties.

Thurmond RL, Desai PJ, Dunford PJ, Fung-Leung WP, Hofstra CL, Jiang W, Nguyen S, Riley JP, Sun S, Williams KN, Edwards JP, Karlsson L. Thurmond RL, et al. Among authors: sun s. J Pharmacol Exp Ther. 2004 Apr;309(1):404-13. doi: 10.1124/jpet.103.061754. Epub 2004 Jan 13. J Pharmacol Exp Ther. 2004. PMID: 14722321

4

Nonpeptidic, noncovalent inhibitors of the cysteine protease cathepsin S.

Thurmond RL, Beavers MP, Cai H, Meduna SP, Gustin DJ, Sun S, Almond HJ, Karlsson L, Edwards JP. Thurmond RL, et al. Among authors: sun s. J Med Chem. 2004 Sep 23;47(20):4799-801. doi: 10.1021/jm0496133. J Med Chem. 2004. PMID: 15369380

5

Discovery and SAR studies of a novel series of noncovalent cathepsin S inhibitors.

Gustin DJ, Sehon CA, Wei J, Cai H, Meduna SP, Khatuya H, Sun S, Gu Y, Jiang W, Thurmond RL, Karlsson L, Edwards JP. Gustin DJ, et al. Among authors: sun s. Bioorg Med Chem Lett. 2005 Mar 15;15(6):1687-91. doi: 10.1016/j.bmcl.2005.01.045. Bioorg Med Chem Lett. 2005. PMID: 15745822

6

Cathepsin S inhibitors as novel immunomodulators.

Thurmond RL, Sun S, Karlsson L, Edwards JP. Thurmond RL, et al. Among authors: sun s. Curr Opin Investig Drugs. 2005 May;6(5):473-82. Curr Opin Investig Drugs. 2005. PMID: 15912960 Review.

7

The SAR of 4-substituted (6,6-bicyclic) piperidine cathepsin S inhibitors.

Grice CA, Tays K, Khatuya H, Gustin DJ, Butler CR, Wei J, Sehon CA, Sun S, Gu Y, Jiang W, Thurmond RL, Karlsson L, Edwards JP. Grice CA, et al. Among authors: sun s. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2209-12. doi: 10.1016/j.bmcl.2006.01.038. Epub 2006 Feb 3. Bioorg Med Chem Lett. 2006. PMID: 16458510

8

Pyrazole-based cathepsin S inhibitors with improved cellular potency.

Wei J, Pio BA, Cai H, Meduna SP, Sun S, Gu Y, Jiang W, Thurmond RL, Karlsson L, Edwards JP. Wei J, et al. Among authors: sun s. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5525-8. doi: 10.1016/j.bmcl.2007.08.038. Epub 2007 Aug 22. Bioorg Med Chem Lett. 2007. PMID: 17822900

9

TLR7/9 antagonists as therapeutics for immune-mediated inflammatory disorders.

Sun S, Rao NL, Venable J, Thurmond R, Karlsson L. Sun S, et al. Inflamm Allergy Drug Targets. 2007 Dec;6(4):223-35. doi: 10.2174/187152807783334300. Inflamm Allergy Drug Targets. 2007. PMID: 18220957 Review.

10

Pyrazole-based cathepsin S inhibitors with arylalkynes as P1 binding elements.

Ameriks MK, Axe FU, Bembenek SD, Edwards JP, Gu Y, Karlsson L, Randal M, Sun S, Thurmond RL, Zhu J. Ameriks MK, et al. Among authors: sun s. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6131-4. doi: 10.1016/j.bmcl.2009.09.014. Epub 2009 Sep 10. Bioorg Med Chem Lett. 2009. PMID: 19773165

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