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The snake venom toxin alboaggregin-A activates glycoprotein VI.
Asazuma N, Marshall SJ, Berlanga O, Snell D, Poole AW, Berndt MC, Andrews RK, Watson SP. Asazuma N, et al. Among authors: berndt mc. Blood. 2001 Jun 15;97(12):3989-91. doi: 10.1182/blood.v97.12.3989. Blood. 2001. PMID: 11389045 Free article.
Constitutive dimerization of glycoprotein VI (GPVI) in resting platelets is essential for binding to collagen and activation in flowing blood.
Jung SM, Moroi M, Soejima K, Nakagaki T, Miura Y, Berndt MC, Gardiner EE, Howes JM, Pugh N, Bihan D, Watson SP, Farndale RW. Jung SM, et al. Among authors: berndt mc. J Biol Chem. 2012 Aug 24;287(35):30000-13. doi: 10.1074/jbc.M112.359125. Epub 2012 Jul 6. J Biol Chem. 2012. PMID: 22773837 Free PMC article. Clinical Trial.
275 results