Redelinghuys P - Search Results

1

Synthesis and molecular modeling of a lisinopril-tryptophan analogue inhibitor of angiotensin I-converting enzyme.

Nchinda AT, Chibale K, Redelinghuys P, Sturrock ED. Nchinda AT, et al. Among authors: redelinghuys p. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4616-9. doi: 10.1016/j.bmcl.2006.06.004. Epub 2006 Jun 19. Bioorg Med Chem Lett. 2006. PMID: 16784843

2

The N domain of somatic angiotensin-converting enzyme negatively regulates ectodomain shedding and catalytic activity.

Woodman ZL, Schwager SL, Redelinghuys P, Carmona AK, Ehlers MR, Sturrock ED. Woodman ZL, et al. Among authors: redelinghuys p. Biochem J. 2005 Aug 1;389(Pt 3):739-44. doi: 10.1042/BJ20050187. Biochem J. 2005. PMID: 15813703 Free PMC article.

3

Development of domain-selective angiotensin I-converting enzyme inhibitors.

Redelinghuys P, Nchinda AT, Sturrock ED. Redelinghuys P, et al. Ann N Y Acad Sci. 2005 Nov;1056:160-75. doi: 10.1196/annals.1352.035. Ann N Y Acad Sci. 2005. PMID: 16387685

4

Novel ketomethylene inhibitors of angiotensin I-converting enzyme (ACE): inhibition and molecular modelling.

Redelinghuys P, Nchinda AT, Chibale K, Sturrock ED. Redelinghuys P, et al. Biol Chem. 2006 Apr;387(4):461-6. doi: 10.1515/BC.2006.061. Biol Chem. 2006. PMID: 16606345

5

Synthesis of novel keto-ACE analogues as domain-selective angiotensin I-converting enzyme inhibitors.

Nchinda AT, Chibale K, Redelinghuys P, Sturrock ED. Nchinda AT, et al. Among authors: redelinghuys p. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4612-5. doi: 10.1016/j.bmcl.2006.06.003. Epub 2006 Jun 19. Bioorg Med Chem Lett. 2006. PMID: 16784850

6

Homologous substitution of ACE C-domain regions with N-domain sequences: effect on processing, shedding, and catalytic properties.

Woodman ZL, Schwager SL, Redelinghuys P, Chubb AJ, van der Merwe EL, Ehlers MR, Sturrock ED. Woodman ZL, et al. Among authors: redelinghuys p. Biol Chem. 2006 Aug;387(8):1043-51. doi: 10.1515/BC.2006.129. Biol Chem. 2006. PMID: 16895474

7

The role of glycosylation and domain interactions in the thermal stability of human angiotensin-converting enzyme.

O'Neill HG, Redelinghuys P, Schwager SL, Sturrock ED. O'Neill HG, et al. Among authors: redelinghuys p. Biol Chem. 2008 Sep;389(9):1153-61. doi: 10.1515/BC.2008.131. Biol Chem. 2008. PMID: 18713002

8

The N domain of human angiotensin-I-converting enzyme: the role of N-glycosylation and the crystal structure in complex with an N domain-specific phosphinic inhibitor, RXP407.

Anthony CS, Corradi HR, Schwager SL, Redelinghuys P, Georgiadis D, Dive V, Acharya KR, Sturrock ED. Anthony CS, et al. Among authors: redelinghuys p. J Biol Chem. 2010 Nov 12;285(46):35685-93. doi: 10.1074/jbc.M110.167866. Epub 2010 Sep 8. J Biol Chem. 2010. PMID: 20826823 Free PMC article.

9

Deglycosylation, processing and crystallization of human testis angiotensin-converting enzyme.

Gordon K, Redelinghuys P, Schwager SL, Ehlers MR, Papageorgiou AC, Natesh R, Acharya KR, Sturrock ED. Gordon K, et al. Among authors: redelinghuys p. Biochem J. 2003 Apr 15;371(Pt 2):437-42. doi: 10.1042/BJ20021842. Biochem J. 2003. PMID: 12542396 Free PMC article.

10

Early murine T-lymphocyte activation is accompanied by a switch from N-Glycolyl- to N-acetyl-neuraminic acid and generation of ligands for siglec-E.

Redelinghuys P, Antonopoulos A, Liu Y, Campanero-Rhodes MA, McKenzie E, Haslam SM, Dell A, Feizi T, Crocker PR. Redelinghuys P, et al. J Biol Chem. 2011 Oct 7;286(40):34522-32. doi: 10.1074/jbc.M111.243410. Epub 2011 Aug 11. J Biol Chem. 2011. PMID: 21835922 Free PMC article.

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