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Creation and screening of a multi-family bacterial oxidoreductase library to discover novel nitroreductases that efficiently activate the bioreductive prodrugs CB1954 and PR-104A.
Prosser GA, Copp JN, Mowday AM, Guise CP, Syddall SP, Williams EM, Horvat CN, Swe PM, Ashoorzadeh A, Denny WA, Smaill JB, Patterson AV, Ackerley DF. Prosser GA, et al. Among authors: swe pm. Biochem Pharmacol. 2013 Apr 15;85(8):1091-103. doi: 10.1016/j.bcp.2013.01.029. Epub 2013 Feb 8. Biochem Pharmacol. 2013. PMID: 23399641
Complement inhibition by Sarcoptes scabiei protects Streptococcus pyogenes - An in vitro study to unravel the molecular mechanisms behind the poorly understood predilection of S. pyogenes to infect mite-induced skin lesions.
Swe PM, Christian LD, Lu HC, Sriprakash KS, Fischer K. Swe PM, et al. PLoS Negl Trop Dis. 2017 Mar 9;11(3):e0005437. doi: 10.1371/journal.pntd.0005437. eCollection 2017 Mar. PLoS Negl Trop Dis. 2017. PMID: 28278252 Free PMC article.
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