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Evolution of a cytokine using DNA family shuffling.
Chang CC, Chen TT, Cox BW, Dawes GN, Stemmer WP, Punnonen J, Patten PA. Chang CC, et al. Among authors: dawes gn. Nat Biotechnol. 1999 Aug;17(8):793-7. doi: 10.1038/11737. Nat Biotechnol. 1999. PMID: 10429246
Directed evolution of gene-shuffled IFN-alpha molecules with activity profiles tailored for treatment of chronic viral diseases.
Brideau-Andersen AD, Huang X, Sun SC, Chen TT, Stark D, Sas IJ, Zadik L, Dawes GN, Guptill DR, McCord R, Govindarajan S, Roy A, Yang S, Gao J, Chen YH, Skartved NJ, Pedersen AK, Lin D, Locher CP, Rebbapragada I, Jensen AD, Bass SH, Nissen TL, Viswanathan S, Foster GR, Symons JA, Patten PA. Brideau-Andersen AD, et al. Proc Natl Acad Sci U S A. 2007 May 15;104(20):8269-74. doi: 10.1073/pnas.0609001104. Epub 2007 May 9. Proc Natl Acad Sci U S A. 2007. PMID: 17494769 Free PMC article.
Molecular breeding of viruses.
Soong NW, Nomura L, Pekrun K, Reed M, Sheppard L, Dawes G, Stemmer WP. Soong NW, et al. Among authors: dawes g. Nat Genet. 2000 Aug;25(4):436-9. doi: 10.1038/78132. Nat Genet. 2000. PMID: 10932190
229 results