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Cancer genes hypermethylated in human embryonic stem cells.
Calvanese V, Horrillo A, Hmadcha A, Suarez-Alvarez B, Fernandez AF, Lara E, Casado S, Menendez P, Bueno C, Garcia-Castro J, Rubio R, Lapunzina P, Alaminos M, Borghese L, Terstegge S, Harrison NJ, Moore HD, Brüstle O, Lopez-Larrea C, Andrews PW, Soria B, Esteller M, Fraga MF. Calvanese V, et al. Among authors: lara e. PLoS One. 2008 Sep 29;3(9):e3294. doi: 10.1371/journal.pone.0003294. PLoS One. 2008. PMID: 18820729 Free PMC article.
The role of epigenetics in aging and age-related diseases.
Calvanese V, Lara E, Kahn A, Fraga MF. Calvanese V, et al. Among authors: lara e. Ageing Res Rev. 2009 Oct;8(4):268-76. doi: 10.1016/j.arr.2009.03.004. Epub 2009 Apr 1. Ageing Res Rev. 2009. PMID: 19716530 Review.
Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect.
Lara E, Mai A, Calvanese V, Altucci L, Lopez-Nieva P, Martinez-Chantar ML, Varela-Rey M, Rotili D, Nebbioso A, Ropero S, Montoya G, Oyarzabal J, Velasco S, Serrano M, Witt M, Villar-Garea A, Imhof A, Mato JM, Esteller M, Fraga MF. Lara E, et al. Oncogene. 2009 Feb 12;28(6):781-91. doi: 10.1038/onc.2008.436. Epub 2008 Dec 8. Oncogene. 2009. PMID: 19060927
Effects of short-term high-fat overfeeding on genome-wide DNA methylation in the skeletal muscle of healthy young men.
Jacobsen SC, Brøns C, Bork-Jensen J, Ribel-Madsen R, Yang B, Lara E, Hall E, Calvanese V, Nilsson E, Jørgensen SW, Mandrup S, Ling C, Fernandez AF, Fraga MF, Poulsen P, Vaag A. Jacobsen SC, et al. Among authors: lara e. Diabetologia. 2012 Dec;55(12):3341-9. doi: 10.1007/s00125-012-2717-8. Epub 2012 Sep 8. Diabetologia. 2012. PMID: 22961225 Clinical Trial.
Genome-wide analysis of DNA methylation differences in muscle and fat from monozygotic twins discordant for type 2 diabetes.
Ribel-Madsen R, Fraga MF, Jacobsen S, Bork-Jensen J, Lara E, Calvanese V, Fernandez AF, Friedrichsen M, Vind BF, Højlund K, Beck-Nielsen H, Esteller M, Vaag A, Poulsen P. Ribel-Madsen R, et al. Among authors: lara e. PLoS One. 2012;7(12):e51302. doi: 10.1371/journal.pone.0051302. Epub 2012 Dec 10. PLoS One. 2012. PMID: 23251491 Free PMC article.
Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells.
Rotili D, Tarantino D, Nebbioso A, Paolini C, Huidobro C, Lara E, Mellini P, Lenoci A, Pezzi R, Botta G, Lahtela-Kakkonen M, Poso A, Steinkühler C, Gallinari P, De Maria R, Fraga M, Esteller M, Altucci L, Mai A. Rotili D, et al. Among authors: lara e. J Med Chem. 2012 Dec 27;55(24):10937-47. doi: 10.1021/jm3011614. Epub 2012 Dec 12. J Med Chem. 2012. PMID: 23189967
324 results