Schaeffer MT - Search Results

1

Disulfide bonds are neither required, present, nor compatible with full activity of human recombinant acidic fibroblast growth factor.

Linemeyer DL, Menke JG, Kelly LJ, DiSalvo J, Soderman D, Schaeffer MT, Ortega S, Gimenez-Gallego G, Thomas KA. Linemeyer DL, et al. Among authors: schaeffer mt. Growth Factors. 1990;3(4):287-98. doi: 10.3109/08977199009003671. Growth Factors. 1990. PMID: 1701652

2

Conversion of cysteine to serine residues alters the activity, stability, and heparin dependence of acidic fibroblast growth factor.

Ortega S, Schaeffer MT, Soderman D, DiSalvo J, Linemeyer DL, Gimenez-Gallego G, Thomas KA. Ortega S, et al. Among authors: schaeffer mt. J Biol Chem. 1991 Mar 25;266(9):5842-6. J Biol Chem. 1991. PMID: 1706340 Free article.

3

Structural modifications of acidic fibroblast growth factor alter activity, stability, and heparin dependence.

Thomas KA, Ortega S, Soderman D, Schaeffer MT, DiSalvo J, Gimenez-Gallego G, Linemeyer D, Kelly L, Menke J. Thomas KA, et al. Among authors: schaeffer mt. Ann N Y Acad Sci. 1991;638:9-17. doi: 10.1111/j.1749-6632.1991.tb49013.x. Ann N Y Acad Sci. 1991. PMID: 1723866 No abstract available.

4

Purification of a glycoprotein vascular endothelial cell mitogen from a rat glioma-derived cell line.

Conn G, Soderman DD, Schaeffer MT, Wile M, Hatcher VB, Thomas KA. Conn G, et al. Among authors: schaeffer mt. Proc Natl Acad Sci U S A. 1990 Feb;87(4):1323-7. doi: 10.1073/pnas.87.4.1323. Proc Natl Acad Sci U S A. 1990. PMID: 2406719 Free PMC article.

5

Desensitization of beta3-adrenergic receptor-stimulated adenylyl cyclase activity and lipolysis in rats.

Vicario PP, Candelore MR, Schaeffer MT, Kelly L, Thompson GM, Brady EJ, Saperstein R, MacIntyre DE, Tota LM, Cascieri MA. Vicario PP, et al. Among authors: schaeffer mt. Life Sci. 1998;62(7):627-38. doi: 10.1016/s0024-3205(97)01158-2. Life Sci. 1998. PMID: 9472722

6

Synthesis and activity of 4,5-diarylimidazoles as human CB1 receptor inverse agonists.

Plummer CW, Finke PE, Mills SG, Wang J, Tong X, Doss GA, Fong TM, Lao JZ, Schaeffer MT, Chen J, Shen CP, Stribling DS, Shearman LP, Strack AM, Van der Ploeg LH. Plummer CW, et al. Among authors: schaeffer mt. Bioorg Med Chem Lett. 2005 Mar 1;15(5):1441-6. doi: 10.1016/j.bmcl.2004.12.078. Bioorg Med Chem Lett. 2005. PMID: 15713403

7

Use of bioluminescent aequorin for the pharmacological characterization of 5HT receptors.

Schaeffer MT, Cully D, Chou M, Liu J, Van der Ploeg LH, Fong TM. Schaeffer MT, et al. J Recept Signal Transduct Res. 1999 Nov;19(6):927-38. doi: 10.3109/10799899909038432. J Recept Signal Transduct Res. 1999. PMID: 10533981

8

Molecular basis of the pharmacological difference between rat and human bombesin receptor subtype-3 (BRS-3).

Liu J, Lao ZJ, Zhang J, Schaeffer MT, Jiang MM, Guan XM, Van der Ploeg LH, Fong TM. Liu J, et al. Among authors: schaeffer mt. Biochemistry. 2002 Jul 16;41(28):8954-60. doi: 10.1021/bi0202777. Biochemistry. 2002. PMID: 12102638

9

Synthesis and SAR of 5,6-diarylpyridines as human CB1 inverse agonists.

Meurer LC, Finke PE, Mills SG, Walsh TF, Toupence RB, Debenham JS, Goulet MT, Wang J, Tong X, Fong TM, Lao J, Schaeffer MT, Chen J, Shen CP, Sloan Stribling D, Shearman LP, Strack AM, Van der Ploeg LH. Meurer LC, et al. Among authors: schaeffer mt. Bioorg Med Chem Lett. 2005 Feb 1;15(3):645-51. doi: 10.1016/j.bmcl.2004.11.031. Bioorg Med Chem Lett. 2005. PMID: 15664830

10

Synthesis of functionalized 1,8-naphthyridinones and their evaluation as novel, orally active CB1 receptor inverse agonists.

Debenham JS, Madsen-Duggan CB, Walsh TF, Wang J, Tong X, Doss GA, Lao J, Fong TM, Schaeffer MT, Xiao JC, Huang CR, Shen CP, Feng Y, Marsh DJ, Stribling DS, Shearman LP, Strack AM, MacIntyre DE, Van der Ploeg LH, Goulet MT. Debenham JS, et al. Among authors: schaeffer mt. Bioorg Med Chem Lett. 2006 Feb;16(3):681-5. doi: 10.1016/j.bmcl.2005.10.028. Epub 2005 Nov 2. Bioorg Med Chem Lett. 2006. PMID: 16263284

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