Haasen D - Search Results

1

G protein-coupled receptor internalization assays in the high-content screening format.

Haasen D, Schnapp A, Valler MJ, Heilker R. Haasen D, et al. Methods Enzymol. 2006;414:121-39. doi: 10.1016/S0076-6879(06)14008-2. Methods Enzymol. 2006. PMID: 17110190

2

Comparison of G-protein coupled receptor desensitization-related beta-arrestin redistribution using confocal and non-confocal imaging.

Haasen D, Wolff M, Valler MJ, Heilker R. Haasen D, et al. Comb Chem High Throughput Screen. 2006 Jan;9(1):37-47. doi: 10.2174/138620706775213921. Comb Chem High Throughput Screen. 2006. PMID: 16454685

3

Automated high content screening for phosphoinositide 3 kinase inhibition using an AKT 1 redistribution assay.

Wolff M, Haasen D, Merk S, Kroner M, Maier U, Bordel S, Wiedenmann J, Nienhaus GU, Valler M, Heilker R. Wolff M, et al. Among authors: haasen d. Comb Chem High Throughput Screen. 2006 Jun;9(5):339-50. doi: 10.2174/138620706777452447. Comb Chem High Throughput Screen. 2006. PMID: 16787147

4

Pharmacological profiling of chemokine receptor-directed compounds using high-content screening.

Haasen D, Merk S, Seither P, Martyres D, Hobbie S, Heilker R. Haasen D, et al. J Biomol Screen. 2008 Jan;13(1):40-53. doi: 10.1177/1087057107312128. J Biomol Screen. 2008. PMID: 18227225

5

High content screening of CXCR2-dependent signalling pathways.

Wolff M, Kredel S, Haasen D, Wiedenmann J, Nienhaus GU, Kistler B, Oswald F, Heilker R. Wolff M, et al. Among authors: haasen d. Comb Chem High Throughput Screen. 2010 Jan;13(1):3-15. doi: 10.2174/138620710790218249. Comb Chem High Throughput Screen. 2010. PMID: 20214572

6

Different species of alpha-synuclein oligomers induce calcium influx and seeding.

Danzer KM, Haasen D, Karow AR, Moussaud S, Habeck M, Giese A, Kretzschmar H, Hengerer B, Kostka M. Danzer KM, et al. Among authors: haasen d. J Neurosci. 2007 Aug 22;27(34):9220-32. doi: 10.1523/JNEUROSCI.2617-07.2007. J Neurosci. 2007. PMID: 17715357 Free PMC article.

7

Characterization of kinase inhibitors using reverse phase protein arrays.

Martiny-Baron G, Haasen D, D'Dorazio D, Voshol J, Fabbro D. Martiny-Baron G, et al. Among authors: haasen d. Methods Mol Biol. 2011;785:79-107. doi: 10.1007/978-1-61779-286-1_7. Methods Mol Biol. 2011. PMID: 21901595

8

Identification and optimisation of a 4',5-bisthiazole series of selective phosphatidylinositol-3 kinase alpha inhibitors.

Fairhurst RA, Imbach-Weese P, Gerspacher M, Caravatti G, Furet P, Zoller T, Fritsch C, Haasen D, Trappe J, Guthy DA, Arz D, Wirth J. Fairhurst RA, et al. Among authors: haasen d. Bioorg Med Chem Lett. 2015 Sep 1;25(17):3569-74. doi: 10.1016/j.bmcl.2015.06.078. Epub 2015 Jun 27. Bioorg Med Chem Lett. 2015. PMID: 26206504

9

Discovery of novel pyrrolidineoxy-substituted heteroaromatics as potent and selective PI3K delta inhibitors with improved physicochemical properties.

Hoegenauer K, Soldermann N, Hebach C, Hollingworth GJ, Lewis I, von Matt A, Smith AB, Wolf RM, Wilcken R, Haasen D, Burkhart C, Zécri F. Hoegenauer K, et al. Among authors: haasen d. Bioorg Med Chem Lett. 2016 Dec 1;26(23):5657-5662. doi: 10.1016/j.bmcl.2016.10.069. Epub 2016 Oct 27. Bioorg Med Chem Lett. 2016. PMID: 27816514

10

A drug resistance screen using a selective MET inhibitor reveals a spectrum of mutations that partially overlap with activating mutations found in cancer patients.

Tiedt R, Degenkolbe E, Furet P, Appleton BA, Wagner S, Schoepfer J, Buck E, Ruddy DA, Monahan JE, Jones MD, Blank J, Haasen D, Drueckes P, Wartmann M, McCarthy C, Sellers WR, Hofmann F. Tiedt R, et al. Among authors: haasen d. Cancer Res. 2011 Aug 1;71(15):5255-64. doi: 10.1158/0008-5472.CAN-10-4433. Epub 2011 Jun 22. Cancer Res. 2011. PMID: 21697284

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