Kavanagh KL - Search Results

1

Reversible sequestration of active site cysteines in a 2Fe-2S-bridged dimer provides a mechanism for glutaredoxin 2 regulation in human mitochondria.

Johansson C, Kavanagh KL, Gileadi O, Oppermann U. Johansson C, et al. Among authors: kavanagh kl. J Biol Chem. 2007 Feb 2;282(5):3077-82. doi: 10.1074/jbc.M608179200. Epub 2006 Nov 22. J Biol Chem. 2007. PMID: 17121859 Free article.

2

Structure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum disease.

McDonough MA, Kavanagh KL, Butler D, Searls T, Oppermann U, Schofield CJ. McDonough MA, et al. Among authors: kavanagh kl. J Biol Chem. 2005 Dec 9;280(49):41101-10. doi: 10.1074/jbc.M507528200. Epub 2005 Sep 25. J Biol Chem. 2005. PMID: 16186124 Free article.

3

The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding.

Kavanagh KL, Dunford JE, Bunkoczi G, Russell RGG, Oppermann U. Kavanagh KL, et al. J Biol Chem. 2006 Aug 4;281(31):22004-22012. doi: 10.1074/jbc.M602603200. Epub 2006 May 11. J Biol Chem. 2006. PMID: 16698791 Free article.

4

The crystal structure of human GLRX5: iron-sulfur cluster co-ordination, tetrameric assembly and monomer activity.

Johansson C, Roos AK, Montano SJ, Sengupta R, Filippakopoulos P, Guo K, von Delft F, Holmgren A, Oppermann U, Kavanagh KL. Johansson C, et al. Among authors: kavanagh kl. Biochem J. 2011 Jan 15;433(2):303-11. doi: 10.1042/BJ20101286. Biochem J. 2011. PMID: 21029046

5

Structural basis of fumarate hydratase deficiency.

Picaud S, Kavanagh KL, Yue WW, Lee WH, Muller-Knapp S, Gileadi O, Sacchettini J, Oppermann U. Picaud S, et al. Among authors: kavanagh kl. J Inherit Metab Dis. 2011 Jun;34(3):671-6. doi: 10.1007/s10545-011-9294-8. Epub 2011 Mar 29. J Inherit Metab Dis. 2011. PMID: 21445611 Free PMC article.

6

Structure and mechanism of human UDP-glucose 6-dehydrogenase.

Egger S, Chaikuad A, Kavanagh KL, Oppermann U, Nidetzky B. Egger S, et al. Among authors: kavanagh kl. J Biol Chem. 2011 Jul 8;286(27):23877-87. doi: 10.1074/jbc.M111.234682. Epub 2011 Apr 18. J Biol Chem. 2011. PMID: 21502315 Free PMC article.

7

Structure of human aspartyl aminopeptidase complexed with substrate analogue: insight into catalytic mechanism, substrate specificity and M18 peptidase family.

Chaikuad A, Pilka ES, De Riso A, von Delft F, Kavanagh KL, Vénien-Bryan C, Oppermann U, Yue WW. Chaikuad A, et al. Among authors: kavanagh kl. BMC Struct Biol. 2012 Jun 21;12:14. doi: 10.1186/1472-6807-12-14. BMC Struct Biol. 2012. PMID: 22720794 Free PMC article.

8

Structural and biochemical characterization of human orphan DHRS10 reveals a novel cytosolic enzyme with steroid dehydrogenase activity.

Lukacik P, Keller B, Bunkoczi G, Kavanagh KL, Lee WH, Adamski J, Oppermann U. Lukacik P, et al. Among authors: kavanagh kl. Biochem J. 2007 Mar 15;402(3):419-27. doi: 10.1042/BJ20061319. Biochem J. 2007. PMID: 17067289 Free PMC article.

9

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.

Ng SS, Kavanagh KL, McDonough MA, Butler D, Pilka ES, Lienard BM, Bray JE, Savitsky P, Gileadi O, von Delft F, Rose NR, Offer J, Scheinost JC, Borowski T, Sundstrom M, Schofield CJ, Oppermann U. Ng SS, et al. Among authors: kavanagh kl. Nature. 2007 Jul 5;448(7149):87-91. doi: 10.1038/nature05971. Epub 2007 Jun 24. Nature. 2007. PMID: 17589501

10

Mechanism and substrate recognition of human holo ACP synthase.

Bunkoczi G, Pasta S, Joshi A, Wu X, Kavanagh KL, Smith S, Oppermann U. Bunkoczi G, et al. Among authors: kavanagh kl. Chem Biol. 2007 Nov;14(11):1243-53. doi: 10.1016/j.chembiol.2007.10.013. Chem Biol. 2007. PMID: 18022563 Free PMC article.

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