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Cyclosporin A and FK506 inhibit IL-12p40 production through the calmodulin/calmodulin-dependent protein kinase-activated phosphoinositide 3-kinase in lipopolysaccharide-stimulated human monocytic cells.
Ma W, Mishra S, Gee K, Mishra JP, Nandan D, Reiner NE, Angel JB, Kumar A. Ma W, et al. Among authors: angel jb. J Biol Chem. 2007 May 4;282(18):13351-62. doi: 10.1074/jbc.M611522200. Epub 2007 Mar 8. J Biol Chem. 2007. Retraction in: J Biol Chem. 2012 Jan 2;287(1):804. doi: 10.1074/jbc.A111.611522. PMID: 17347151 Free article. Retracted.
Engagement of CD14 sensitizes primary monocytes to IFN-γ to produce IL-12/23p40 and IL-23 through p38 mitogen-activated protein kinase and independent of the janus kinase/signal transducers and activators of transcription signaling.
Blahoianu MA, Rahimi AA, Gajanayaka N, Kozlowski M, Angel JB, Kumar A. Blahoianu MA, et al. Among authors: angel jb. J Interferon Cytokine Res. 2013 Aug;33(8):434-45. doi: 10.1089/jir.2012.0058. Epub 2013 May 16. J Interferon Cytokine Res. 2013. PMID: 23679818
201 results