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Enhanced cytotoxicity with a novel system combining the paclitaxel-2'-ethylcarbonate prodrug and an HSV amplicon with an attenuated replication-competent virus, HF10 as a helper virus.
Ishida D, Nawa A, Tanino T, Goshima F, Luo CH, Iwaki M, Kajiyama H, Shibata K, Yamamoto E, Ino K, Tsurumi T, Nishiyama Y, Kikkawa F. Ishida D, et al. Among authors: nishiyama y. Cancer Lett. 2010 Feb 1;288(1):17-27. doi: 10.1016/j.canlet.2009.06.014. Epub 2009 Jul 14. Cancer Lett. 2010. PMID: 19604626
., Oncolytic viral therapy using a spontaneously generated herpes simplex virus type 1 variant for disseminated peritoneal tumor in immunocompetent mice, Arch. Virol. 148 (2003) 813-825; S. Kohno, C. Lou, F. Goshima, Y. Nishiyama, T. Sata, Y. Ono, Herpes simp …
., Oncolytic viral therapy using a spontaneously generated herpes simplex virus type 1 variant for disseminated peritoneal tumor in immunoco …
Herpes simplex virus UL14 protein blocks apoptosis.
Yamauchi Y, Daikoku T, Goshima F, Nishiyama Y. Yamauchi Y, et al. Among authors: nishiyama y. Microbiol Immunol. 2003;47(9):685-9. doi: 10.1111/j.1348-0421.2003.tb03432.x. Microbiol Immunol. 2003. PMID: 14584616 Free article.
Inhibition of S-phase cyclin-dependent kinase activity blocks expression of Epstein-Barr virus immediate-early and early genes, preventing viral lytic replication.
Kudoh A, Daikoku T, Sugaya Y, Isomura H, Fujita M, Kiyono T, Nishiyama Y, Tsurumi T. Kudoh A, et al. Among authors: nishiyama y. J Virol. 2004 Jan;78(1):104-15. doi: 10.1128/jvi.78.1.104-115.2004. J Virol. 2004. PMID: 14671092 Free PMC article.
The induction of lytic replication of the Epstein-Barr virus (EBV) completely arrests cell cycle progression, in spite of elevation of S-phase cyclin-dependent kinase (CDK) activity, thereby causing accumulation of hyperphosphorylated forms of retinoblastoma (Rb) protein (A. Kudo …
The induction of lytic replication of the Epstein-Barr virus (EBV) completely arrests cell cycle progression, in spite of elevation of S-pha …
1,777 results