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Assessing and managing toxicities induced by kinase inhibitors.
Curr Opin Drug Discov Devel. 2007 Jan;10(1):53-7.
Curr Opin Drug Discov Devel. 2007.
PMID: 17265742
Review.
Predicting myelosuppression of drugs from in silico models.
Crivori P, Pennella G, Magistrelli M, Grossi P, Giusti AM.
Crivori P, et al. Among authors: pennella g.
J Chem Inf Model. 2011 Feb 28;51(2):434-45. doi: 10.1021/ci1003834. Epub 2011 Jan 28.
J Chem Inf Model. 2011.
PMID: 21275392
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Decreased tyrosine phosphorylation in tumour cells resistant to FCE 24517 (tallimustine).
Ciomei M, Pastori W, Capolongo L, Geroni C, Melegaro G, Pennella G, Grandi M.
Ciomei M, et al. Among authors: pennella g.
Br J Cancer. 1995 Dec;72(6):1504-8. doi: 10.1038/bjc.1995.537.
Br J Cancer. 1995.
PMID: 8519667
Free PMC article.
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L1210 cells selected for resistance to methoxymorpholinyl doxorubicin appear specifically resistant to this class of morpholinyl derivatives.
Geroni C, Pesenti E, Broggini M, Belvedere G, Tagliabue G, D'Incalci M, Pennella G, Grandi M.
Geroni C, et al. Among authors: pennella g.
Br J Cancer. 1994 Feb;69(2):315-9. doi: 10.1038/bjc.1994.57.
Br J Cancer. 1994.
PMID: 8297727
Free PMC article.
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Cytotoxic alpha-bromoacrylic derivatives of distamycin analogues modified at the amidino moiety.
Cozzi P, Beria I, Caldarelli M, Geroni C, Mongelli N, Pennella G.
Cozzi P, et al. Among authors: pennella g.
Bioorg Med Chem Lett. 2000 Jun 5;10(11):1273-6. doi: 10.1016/s0960-894x(00)00205-5.
Bioorg Med Chem Lett. 2000.
PMID: 10866398
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4-Demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548), a novel anticancer agent active against tumor cell lines with different resistance mechanisms.
Marchini S, Damia G, Broggini M, Pennella G, Ripamonti M, Marsiglio A, Geroni C.
Marchini S, et al. Among authors: pennella g.
Cancer Res. 2001 Mar 1;61(5):1991-5.
Cancer Res. 2001.
PMID: 11280757
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Hematotoxicity on human bone marrow- and umbilical cord blood-derived progenitor cells and in vitro therapeutic index of methoxymorpholinyldoxorubicin and its metabolites.
Ghielmini M, Colli E, Bosshard G, Pennella G, Geroni C, Torri V, D'Incalci M, Cavalli F, Sessa C.
Ghielmini M, et al. Among authors: pennella g.
Cancer Chemother Pharmacol. 1998;42(3):235-40. doi: 10.1007/s002800050810.
Cancer Chemother Pharmacol. 1998.
PMID: 9685059
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