Uchiyama Y - Search Results

1

Cathepsin D deficiency induces persistent neurodegeneration in the absence of Bax-dependent apoptosis.

Shacka JJ, Klocke BJ, Young C, Shibata M, Olney JW, Uchiyama Y, Saftig P, Roth KA. Shacka JJ, et al. Among authors: uchiyama y. J Neurosci. 2007 Feb 21;27(8):2081-90. doi: 10.1523/JNEUROSCI.5577-06.2007. J Neurosci. 2007. PMID: 17314303 Free PMC article.

2

Altered regulation of phosphatidylinositol 3-kinase signaling in cathepsin D-deficient brain.

Walls KC, Klocke BJ, Saftig P, Shibata M, Uchiyama Y, Roth KA, Shacka JJ. Walls KC, et al. Among authors: uchiyama y. Autophagy. 2007 May-Jun;3(3):222-9. doi: 10.4161/auto.3822. Epub 2007 May 11. Autophagy. 2007. PMID: 17297299

3

Kainic acid induces early and transient autophagic stress in mouse hippocampus.

Shacka JJ, Lu J, Xie ZL, Uchiyama Y, Roth KA, Zhang J. Shacka JJ, et al. Among authors: uchiyama y. Neurosci Lett. 2007 Feb 27;414(1):57-60. doi: 10.1016/j.neulet.2006.12.025. Epub 2006 Dec 27. Neurosci Lett. 2007. PMID: 17223264 Free PMC article.

4

Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity.

Qiao L, Hamamichi S, Caldwell KA, Caldwell GA, Yacoubian TA, Wilson S, Xie ZL, Speake LD, Parks R, Crabtree D, Liang Q, Crimmins S, Schneider L, Uchiyama Y, Iwatsubo T, Zhou Y, Peng L, Lu Y, Standaert DG, Walls KC, Shacka JJ, Roth KA, Zhang J. Qiao L, et al. Among authors: uchiyama y. Mol Brain. 2008 Nov 21;1:17. doi: 10.1186/1756-6606-1-17. Mol Brain. 2008. PMID: 19021916 Free PMC article.

5

Differences in expression patterns of cathepsin C/dipeptidyl peptidase I in normal, pathological and aged mouse central nervous system.

Koike M, Shibata M, Ezaki J, Peters C, Saftig P, Kominami E, Uchiyama Y. Koike M, et al. Among authors: uchiyama y. Eur J Neurosci. 2013 Mar;37(5):816-30. doi: 10.1111/ejn.12096. Epub 2012 Dec 20. Eur J Neurosci. 2013. PMID: 23279039

6

Bafilomycin A1 inhibits chloroquine-induced death of cerebellar granule neurons.

Shacka JJ, Klocke BJ, Shibata M, Uchiyama Y, Datta G, Schmidt RE, Roth KA. Shacka JJ, et al. Among authors: uchiyama y. Mol Pharmacol. 2006 Apr;69(4):1125-36. doi: 10.1124/mol.105.018408. Epub 2006 Jan 3. Mol Pharmacol. 2006. PMID: 16391239

7

Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons.

Koike M, Nakanishi H, Saftig P, Ezaki J, Isahara K, Ohsawa Y, Schulz-Schaeffer W, Watanabe T, Waguri S, Kametaka S, Shibata M, Yamamoto K, Kominami E, Peters C, von Figura K, Uchiyama Y. Koike M, et al. Among authors: uchiyama y. J Neurosci. 2000 Sep 15;20(18):6898-906. doi: 10.1523/JNEUROSCI.20-18-06898.2000. J Neurosci. 2000. PMID: 10995834 Free PMC article.

8

Purkinje Cells Are More Vulnerable to the Specific Depletion of Cathepsin D Than to That of Atg7.

Koike M, Shibata M, Sunabori T, Yamaguchi J, Sakimura K, Komatsu M, Tanaka K, Uchiyama Y. Koike M, et al. Among authors: uchiyama y. Am J Pathol. 2017 Jul;187(7):1586-1600. doi: 10.1016/j.ajpath.2017.02.020. Epub 2017 May 11. Am J Pathol. 2017. PMID: 28502476 Free article.

9

Lack of Cathepsin D in the central nervous system results in microglia and astrocyte activation and the accumulation of proteinopathy-related proteins.

Suzuki C, Yamaguchi J, Sanada T, Oliva Trejo JA, Kakuta S, Shibata M, Tanida I, Uchiyama Y. Suzuki C, et al. Among authors: uchiyama y. Sci Rep. 2022 Jul 8;12(1):11662. doi: 10.1038/s41598-022-15805-3. Sci Rep. 2022. PMID: 35804072 Free PMC article.

10

Developing postmitotic mammalian neurons in vivo lacking Apaf-1 undergo programmed cell death by a caspase-independent, nonapoptotic pathway involving autophagy.

Oppenheim RW, Blomgren K, Ethell DW, Koike M, Komatsu M, Prevette D, Roth KA, Uchiyama Y, Vinsant S, Zhu C. Oppenheim RW, et al. Among authors: uchiyama y. J Neurosci. 2008 Feb 6;28(6):1490-7. doi: 10.1523/JNEUROSCI.4575-07.2008. J Neurosci. 2008. PMID: 18256270 Free PMC article.

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