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How can drug discovery for psychiatric disorders be improved?
Agid Y, Buzsáki G, Diamond DM, Frackowiak R, Giedd J, Girault JA, Grace A, Lambert JJ, Manji H, Mayberg H, Popoli M, Prochiantz A, Richter-Levin G, Somogyi P, Spedding M, Svenningsson P, Weinberger D. Agid Y, et al. Among authors: girault ja. Nat Rev Drug Discov. 2007 Mar;6(3):189-201. doi: 10.1038/nrd2217. Nat Rev Drug Discov. 2007. PMID: 17330070 Review.
DARPP-32: an integrator of neurotransmission.
Svenningsson P, Nishi A, Fisone G, Girault JA, Nairn AC, Greengard P. Svenningsson P, et al. Among authors: girault ja. Annu Rev Pharmacol Toxicol. 2004;44:269-96. doi: 10.1146/annurev.pharmtox.44.101802.121415. Annu Rev Pharmacol Toxicol. 2004. PMID: 14744247 Review.
The role of DARPP-32 in the actions of drugs of abuse.
Nairn AC, Svenningsson P, Nishi A, Fisone G, Girault JA, Greengard P. Nairn AC, et al. Among authors: girault ja. Neuropharmacology. 2004;47 Suppl 1:14-23. doi: 10.1016/j.neuropharm.2004.05.010. Neuropharmacology. 2004. PMID: 15464122 Review.
Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum.
Valjent E, Pascoli V, Svenningsson P, Paul S, Enslen H, Corvol JC, Stipanovich A, Caboche J, Lombroso PJ, Nairn AC, Greengard P, Hervé D, Girault JA. Valjent E, et al. Among authors: girault ja. Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):491-6. doi: 10.1073/pnas.0408305102. Epub 2004 Dec 17. Proc Natl Acad Sci U S A. 2005. PMID: 15608059 Free PMC article.
A phosphatase cascade by which rewarding stimuli control nucleosomal response.
Stipanovich A, Valjent E, Matamales M, Nishi A, Ahn JH, Maroteaux M, Bertran-Gonzalez J, Brami-Cherrier K, Enslen H, Corbillé AG, Filhol O, Nairn AC, Greengard P, Hervé D, Girault JA. Stipanovich A, et al. Among authors: girault ja. Nature. 2008 Jun 12;453(7197):879-84. doi: 10.1038/nature06994. Epub 2008 May 21. Nature. 2008. PMID: 18496528 Free PMC article.
225 results