Löffler M - Search Results

1

Functional expression of human dihydroorotate dehydrogenase (DHODH) in pyr4 mutants of ustilago maydis allows target validation of DHODH inhibitors in vivo.

Zameitat E, Freymark G, Dietz CD, Löffler M, Bölker M. Zameitat E, et al. Among authors: loffler m. Appl Environ Microbiol. 2007 May;73(10):3371-9. doi: 10.1128/AEM.02569-06. Epub 2007 Mar 16. Appl Environ Microbiol. 2007. PMID: 17369345 Free PMC article.

2

Two different dihydroorotate dehydrogenases from yeast Saccharomyces kluyveri.

Zameitat E, Knecht W, Piskur J, Löffler M. Zameitat E, et al. Among authors: loffler m. FEBS Lett. 2004 Jun 18;568(1-3):129-34. doi: 10.1016/j.febslet.2004.05.017. FEBS Lett. 2004. PMID: 15196933 Free article.

3

Biochemical characterization of recombinant dihydroorotate dehydrogenase from the opportunistic pathogenic yeast Candida albicans.

Zameitat E, Gojković Z, Knecht W, Piskur J, Löffler M. Zameitat E, et al. Among authors: loffler m. FEBS J. 2006 Jul;273(14):3183-91. doi: 10.1111/j.1742-4658.2006.05327.x. Epub 2006 Jun 15. FEBS J. 2006. PMID: 16774642 Free article.

4

Dihydroorotate dehydrogenase from Saccharomyces cerevisiae: spectroscopic investigations with the recombinant enzyme throw light on catalytic properties and metabolism of fumarate analogues.

Zameitat E, Pierik AJ, Zocher K, Löffler M. Zameitat E, et al. Among authors: loffler m. FEMS Yeast Res. 2007 Sep;7(6):897-904. doi: 10.1111/j.1567-1364.2007.00275.x. Epub 2007 Jul 6. FEMS Yeast Res. 2007. PMID: 17617217

5

Immunocytochemical detection of mitochondrial dihydroorotate dehydrogenase in human spermatozoa.

Dietz C, Hinsch E, Löffler M. Dietz C, et al. Among authors: loffler m. Int J Androl. 2000 Oct;23(5):294-9. doi: 10.1046/j.1365-2605.2000.00246.x. Int J Androl. 2000. PMID: 11012787

6

Pyrimidine pathways in health and disease.

Löffler M, Fairbanks LD, Zameitat E, Marinaki AM, Simmonds HA. Löffler M, et al. Trends Mol Med. 2005 Sep;11(9):430-7. doi: 10.1016/j.molmed.2005.07.003. Trends Mol Med. 2005. PMID: 16098809 Review.

7

Orotic Acid, More Than Just an Intermediate of Pyrimidine de novo Synthesis.

Löffler M, Carrey EA, Zameitat E. Löffler M, et al. J Genet Genomics. 2015 May 20;42(5):207-19. doi: 10.1016/j.jgg.2015.04.001. Epub 2015 Apr 18. J Genet Genomics. 2015. PMID: 26059769 Review.

8

Orotate (orotic acid): An essential and versatile molecule.

Löffler M, Carrey EA, Zameitat E. Löffler M, et al. Nucleosides Nucleotides Nucleic Acids. 2016 Dec;35(10-12):566-577. doi: 10.1080/15257770.2016.1147580. Nucleosides Nucleotides Nucleic Acids. 2016. PMID: 27906623 Review.

9

New perspectives on the roles of pyrimidines in the central nervous system.

Löffler M, Carrey EA, Zameitat E. Löffler M, et al. Nucleosides Nucleotides Nucleic Acids. 2018;37(5):290-306. doi: 10.1080/15257770.2018.1453076. Epub 2018 Apr 25. Nucleosides Nucleotides Nucleic Acids. 2018. PMID: 29693489 Review.

10

Drosophila melanogaster dihydroorotate dehydrogenase: the N-terminus is important for biological function in vivo but not for catalytic properties in vitro.

Löffler M, Knecht W, Rawls J, Ullrich A, Dietz C. Löffler M, et al. Insect Biochem Mol Biol. 2002 Sep;32(9):1159-69. doi: 10.1016/s0965-1748(02)00052-8. Insect Biochem Mol Biol. 2002. PMID: 12213251

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