Cavender D - Search Results

1

Different approaches to study mast cell functions.

Sur R, Cavender D, Malaviya R. Sur R, et al. Among authors: cavender d. Int Immunopharmacol. 2007 May;7(5):555-67. doi: 10.1016/j.intimp.2007.01.009. Epub 2007 Feb 14. Int Immunopharmacol. 2007. PMID: 17386403 Review.

2

Role of Janus kinase-2 in IgE receptor-mediated leukotriene C4 production by mast cells.

Sur R, Hall J, Cavender D, Malaviya R. Sur R, et al. Among authors: cavender d. Biochem Biophys Res Commun. 2009 Dec 18;390(3):786-90. doi: 10.1016/j.bbrc.2009.10.050. Epub 2009 Oct 14. Biochem Biophys Res Commun. 2009. PMID: 19835845

3

Synthetic staurosporines via a ring closing metathesis strategy as potent JAK3 inhibitors and modulators of allergic responses.

Wilson LJ, Malaviya R, Yang C, Argentieri R, Wang B, Chen X, Murray WV, Cavender D. Wilson LJ, et al. Among authors: cavender d. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3333-8. doi: 10.1016/j.bmcl.2009.04.039. Epub 2009 Apr 18. Bioorg Med Chem Lett. 2009. PMID: 19427203

4

Targeting cytosolic phospholipase A2 by arachidonyl trifluoromethyl ketone prevents chronic inflammation in mice.

Malaviya R, Ansell J, Hall L, Fahmy M, Argentieri RL, Olini GC Jr, Pereira DW, Sur R, Cavender D. Malaviya R, et al. Among authors: cavender d. Eur J Pharmacol. 2006 Jun 13;539(3):195-204. doi: 10.1016/j.ejphar.2006.03.018. Epub 2006 Mar 20. Eur J Pharmacol. 2006. PMID: 16712837

5

Simplified staurosporine analogs as potent JAK3 inhibitors.

Yang SM, Malaviya R, Wilson LJ, Argentieri R, Chen X, Yang C, Wang B, Cavender D, Murray WV. Yang SM, et al. Among authors: cavender d. Bioorg Med Chem Lett. 2007 Jan 15;17(2):326-31. doi: 10.1016/j.bmcl.2006.10.062. Epub 2006 Oct 26. Bioorg Med Chem Lett. 2007. PMID: 17088059

6

Potent and selective CC-chemokine receptor-2 (CCR2) antagonists as a potential treatment for asthma.

Lagu B, Gerchak C, Pan M, Hou C, Singer M, Malaviya R, Matheis M, Olini G, Cavender D, Wachter M. Lagu B, et al. Among authors: cavender d. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4382-6. doi: 10.1016/j.bmcl.2007.01.115. Epub 2007 Feb 8. Bioorg Med Chem Lett. 2007. PMID: 17587570

7

Synthesis, structure-activity relationship and in vivo antiinflammatory efficacy of substituted dipiperidines as CCR2 antagonists.

Xia M, Hou C, DeMong DE, Pollack SR, Pan M, Brackley JA, Jain N, Gerchak C, Singer M, Malaviya R, Matheis M, Olini G, Cavender D, Wachter M. Xia M, et al. Among authors: cavender d. J Med Chem. 2007 Nov 15;50(23):5561-3. doi: 10.1021/jm070902b. Epub 2007 Oct 11. J Med Chem. 2007. PMID: 17929797

8

A kinase-dead knock-in mutation in mTOR leads to early embryonic lethality and is dispensable for the immune system in heterozygous mice.

Shor B, Cavender D, Harris C. Shor B, et al. Among authors: cavender d. BMC Immunol. 2009 May 20;10:28. doi: 10.1186/1471-2172-10-28. BMC Immunol. 2009. PMID: 19457267 Free PMC article.

9

Imidazopyrimidines, potent inhibitors of p38 MAP kinase.

Rupert KC, Henry JR, Dodd JH, Wadsworth SA, Cavender DE, Olini GC, Fahmy B, Siekierka JJ. Rupert KC, et al. Bioorg Med Chem Lett. 2003 Feb 10;13(3):347-50. doi: 10.1016/s0960-894x(02)01020-x. Bioorg Med Chem Lett. 2003. PMID: 12565927

10

Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production.

Kanakaraj P, Schafer PH, Cavender DE, Wu Y, Ngo K, Grealish PF, Wadsworth SA, Peterson PA, Siekierka JJ, Harris CA, Fung-Leung WP. Kanakaraj P, et al. Among authors: cavender de. J Exp Med. 1998 Jun 15;187(12):2073-9. doi: 10.1084/jem.187.12.2073. J Exp Med. 1998. PMID: 9625767 Free PMC article.

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