Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

38 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Further modification on phenyl acetic acid based quinolines as liver X receptor modulators.
Hu B, Jetter J, Kaufman D, Singhaus R, Bernotas R, Unwalla R, Quinet E, Savio D, Halpern A, Basso M, Keith J, Clerin V, Chen L, Liu QY, Feingold I, Huselton C, Azam F, Goos-Nilsson A, Wilhelmsson A, Nambi P, Wrobel J. Hu B, et al. Among authors: huselton c. Bioorg Med Chem. 2007 May 15;15(10):3321-33. doi: 10.1016/j.bmc.2007.03.013. Epub 2007 Mar 12. Bioorg Med Chem. 2007. PMID: 17391964
3-(3-Aryloxyaryl)imidazo[1,2-a]pyridine sulfones as liver X receptor agonists.
Singhaus RR, Bernotas RC, Steffan R, Matelan E, Quinet E, Nambi P, Feingold I, Huselton C, Wilhelmsson A, Goos-Nilsson A, Wrobel J. Singhaus RR, et al. Among authors: huselton c. Bioorg Med Chem Lett. 2010 Jan 15;20(2):521-5. doi: 10.1016/j.bmcl.2009.11.098. Epub 2009 Nov 23. Bioorg Med Chem Lett. 2010. PMID: 20005711
1-(3-Aryloxyaryl)benzimidazole sulfones are liver X receptor agonists.
Travins JM, Bernotas RC, Kaufman DH, Quinet E, Nambi P, Feingold I, Huselton C, Wilhelmsson A, Goos-Nilsson A, Wrobel J. Travins JM, et al. Among authors: huselton c. Bioorg Med Chem Lett. 2010 Jan 15;20(2):526-30. doi: 10.1016/j.bmcl.2009.11.099. Epub 2009 Nov 23. Bioorg Med Chem Lett. 2010. PMID: 20006495
Synthesis of 4-(3-biaryl)quinoline sulfones as potent liver X receptor agonists.
Ullrich JW, Morris R, Bernotas RC, Travins JM, Jetter J, Unwalla R, Quinet E, Nambi P, Feingold I, Huselton C, Enroth C, Wilhelmsson A, Goos-Nilsson A, Wrobel J. Ullrich JW, et al. Among authors: huselton c. Bioorg Med Chem Lett. 2010 May 1;20(9):2903-7. doi: 10.1016/j.bmcl.2010.03.031. Epub 2010 Mar 9. Bioorg Med Chem Lett. 2010. PMID: 20382019
Discovery of phenyl acetic acid substituted quinolines as novel liver X receptor agonists for the treatment of atherosclerosis.
Hu B, Collini M, Unwalla R, Miller C, Singhaus R, Quinet E, Savio D, Halpern A, Basso M, Keith J, Clerin V, Chen L, Resmini C, Liu QY, Feingold I, Huselton C, Azam F, Farnegardh M, Enroth C, Bonn T, Goos-Nilsson A, Wilhelmsson A, Nambi P, Wrobel J. Hu B, et al. Among authors: huselton c. J Med Chem. 2006 Oct 19;49(21):6151-4. doi: 10.1021/jm0609566. J Med Chem. 2006. PMID: 17034119
2-phenyl-4-piperazinylbenzimidazoles: orally active inhibitors of the gonadotropin releasing hormone (GnRH) receptor.
Pelletier JC, Chengalvala M, Cottom J, Feingold I, Garrick L, Green D, Hauze D, Huselton C, Jetter J, Kao W, Kopf GS, Lundquist JT 4th, Mann C, Mehlmann J, Rogers J, Shanno L, Wrobel J. Pelletier JC, et al. Among authors: huselton c. Bioorg Med Chem. 2008 Jul 1;16(13):6617-40. doi: 10.1016/j.bmc.2008.05.024. Epub 2008 May 11. Bioorg Med Chem. 2008. PMID: 18511284
Indazole-based liver X receptor (LXR) modulators with maintained atherosclerotic lesion reduction activity but diminished stimulation of hepatic triglyceride synthesis.
Wrobel J, Steffan R, Bowen SM, Magolda R, Matelan E, Unwalla R, Basso M, Clerin V, Gardell SJ, Nambi P, Quinet E, Reminick JI, Vlasuk GP, Wang S, Feingold I, Huselton C, Bonn T, Farnegardh M, Hansson T, Nilsson AG, Wilhelmsson A, Zamaratski E, Evans MJ. Wrobel J, et al. Among authors: huselton c. J Med Chem. 2008 Nov 27;51(22):7161-8. doi: 10.1021/jm800799q. J Med Chem. 2008. PMID: 18973288
Discovery of 6-({4-[2-(4-tert-butylphenyl)-1H-benzimidazol-4-yl]piperazin-1-yl}methyl)quinoxaline (WAY-207024): an orally active antagonist of the gonadotropin releasing hormone receptor (GnRH-R).
Pelletier JC, Chengalvala MV, Cottom JE, Feingold IB, Green DM, Hauze DB, Huselton CA, Jetter JW, Kopf GS, Lundquist JT, Magolda RL, Mann CW, Mehlmann JF, Rogers JF, Shanno LK, Adams WR, Tio CO, Wrobel JE. Pelletier JC, et al. Among authors: huselton ca. J Med Chem. 2009 Apr 9;52(7):2148-52. doi: 10.1021/jm801572m. J Med Chem. 2009. PMID: 19271735
Novel progesterone receptor modulators: 4-aryl-phenylsulfonamides.
McComas C, Cohen J, Huselton C, Marella M, Melenski E, Mugford C, Slayden O, Winneker R, Wrobel J, Yudt MR, Fensome A. McComas C, et al. Among authors: huselton c. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7119-22. doi: 10.1016/j.bmcl.2012.09.077. Epub 2012 Sep 29. Bioorg Med Chem Lett. 2012. PMID: 23079530
Small molecule antagonists of the gonadotropin-releasing hormone (GnRH) receptor: structure-activity relationships of small heterocyclic groups appended to the 2-phenyl-4-piperazinyl-benzimidazole template.
Hauze DB, Chengalvala MV, Cottom JE, Feingold IB, Garrick L, Green DM, Huselton C, Kao W, Kees K, Lundquist JT 4th, Mann CW, Mehlmann JF, Rogers JF, Shanno L, Wrobel J, Pelletier JC. Hauze DB, et al. Among authors: huselton c. Bioorg Med Chem Lett. 2009 Apr 1;19(7):1986-90. doi: 10.1016/j.bmcl.2009.02.043. Epub 2009 Feb 13. Bioorg Med Chem Lett. 2009. PMID: 19251413
38 results