Kuhajda FP - Search Results

1

FDG-PET for pharmacodynamic assessment of the fatty acid synthase inhibitor C75 in an experimental model of lung cancer.

Lee JS, Orita H, Gabrielson K, Alvey S, Hagemann RL, Kuhajda FP, Gabrielson E, Pomper MG. Lee JS, et al. Among authors: kuhajda fp. Pharm Res. 2007 Jun;24(6):1202-7. doi: 10.1007/s11095-007-9264-x. Epub 2007 Apr 3. Pharm Res. 2007. PMID: 17404812

2

Selective inhibition of fatty acid synthase for lung cancer treatment.

Orita H, Coulter J, Lemmon C, Tully E, Vadlamudi A, Medghalchi SM, Kuhajda FP, Gabrielson E. Orita H, et al. Among authors: kuhajda fp. Clin Cancer Res. 2007 Dec 1;13(23):7139-45. doi: 10.1158/1078-0432.CCR-07-1186. Epub 2007 Dec 3. Clin Cancer Res. 2007. PMID: 18056164

3

Inhibiting fatty acid synthase for chemoprevention of chemically induced lung tumors.

Orita H, Coulter J, Tully E, Kuhajda FP, Gabrielson E. Orita H, et al. Among authors: kuhajda fp. Clin Cancer Res. 2008 Apr 15;14(8):2458-64. doi: 10.1158/1078-0432.CCR-07-4177. Clin Cancer Res. 2008. PMID: 18413838

4

Fatty acid synthase and cancer: new application of an old pathway.

Kuhajda FP. Kuhajda FP. Cancer Res. 2006 Jun 15;66(12):5977-80. doi: 10.1158/0008-5472.CAN-05-4673. Cancer Res. 2006. PMID: 16778164 Review.

5

Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells.

Zhou W, Simpson PJ, McFadden JM, Townsend CA, Medghalchi SM, Vadlamudi A, Pinn ML, Ronnett GV, Kuhajda FP. Zhou W, et al. Among authors: kuhajda fp. Cancer Res. 2003 Nov 1;63(21):7330-7. Cancer Res. 2003. PMID: 14612531

6

C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolism.

Landree LE, Hanlon AL, Strong DW, Rumbaugh G, Miller IM, Thupari JN, Connolly EC, Huganir RL, Richardson C, Witters LA, Kuhajda FP, Ronnett GV. Landree LE, et al. Among authors: kuhajda fp. J Biol Chem. 2004 Jan 30;279(5):3817-27. doi: 10.1074/jbc.M310991200. Epub 2003 Nov 13. J Biol Chem. 2004. PMID: 14615481 Free article.

7

C75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated protein kinase.

Kim EK, Miller I, Aja S, Landree LE, Pinn M, McFadden J, Kuhajda FP, Moran TH, Ronnett GV. Kim EK, et al. Among authors: kuhajda fp. J Biol Chem. 2004 May 7;279(19):19970-6. doi: 10.1074/jbc.M402165200. Epub 2004 Mar 17. J Biol Chem. 2004. PMID: 15028725 Free article.

8

Fatty acid synthase inhibitors are chemopreventive for mammary cancer in neu-N transgenic mice.

Alli PM, Pinn ML, Jaffee EM, McFadden JM, Kuhajda FP. Alli PM, et al. Among authors: kuhajda fp. Oncogene. 2005 Jan 6;24(1):39-46. doi: 10.1038/sj.onc.1208174. Oncogene. 2005. PMID: 15489885

9

C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity.

Thupari JN, Landree LE, Ronnett GV, Kuhajda FP. Thupari JN, et al. Among authors: kuhajda fp. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9498-502. doi: 10.1073/pnas.132128899. Epub 2002 Jun 11. Proc Natl Acad Sci U S A. 2002. PMID: 12060712 Free PMC article.

10

The connections between C75 and obesity drug-target pathways.

Kuhajda FP, Landree LE, Ronnett GV. Kuhajda FP, et al. Trends Pharmacol Sci. 2005 Nov;26(11):541-4. doi: 10.1016/j.tips.2005.09.002. Epub 2005 Sep 16. Trends Pharmacol Sci. 2005. PMID: 16169094

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