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Wide spectrum modulation by KP-544 in models relevant for neuronal survival.
Neuroreport. 2007 Apr 16;18(6):571-5. doi: 10.1097/WNR.0b013e328012475c.
Neuroreport. 2007.
PMID: 17413659
Improvement of embryonic dopaminergic neurone survival in culture and after grafting into the striatum of hemiparkinsonian rats by CEP-1347.
Boll JB, Geist MA, Kaminski Schierle GS, Petersen K, Leist M, Vaudano E.
Boll JB, et al. Among authors: geist ma.
J Neurochem. 2004 Feb;88(3):698-707. doi: 10.1046/j.1471-4159.2003.02198.x.
J Neurochem. 2004.
PMID: 14720219
Free article.
Item in Clipboard
A role for mixed lineage kinases in granule cell apoptosis induced by cytoskeletal disruption.
Müller GJ, Geist MA, Veng LM, Willesen MG, Johansen FF, Leist M, Vaudano E.
Müller GJ, et al. Among authors: geist ma.
J Neurochem. 2006 Mar;96(5):1242-52. doi: 10.1111/j.1471-4159.2005.03590.x.
J Neurochem. 2006.
PMID: 16478524
Free article.
Item in Clipboard
Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo.
Erbayraktar S, Grasso G, Sfacteria A, Xie QW, Coleman T, Kreilgaard M, Torup L, Sager T, Erbayraktar Z, Gokmen N, Yilmaz O, Ghezzi P, Villa P, Fratelli M, Casagrande S, Leist M, Helboe L, Gerwein J, Christensen S, Geist MA, Pedersen LØ, Cerami-Hand C, Wuerth JP, Cerami A, Brines M.
Erbayraktar S, et al. Among authors: geist ma.
Proc Natl Acad Sci U S A. 2003 May 27;100(11):6741-6. doi: 10.1073/pnas.1031753100. Epub 2003 May 13.
Proc Natl Acad Sci U S A. 2003.
PMID: 12746497
Free PMC article.
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Open-Label, Multicenter, Phase III Extension Study of Idalopirdine as Adjunctive to Donepezil for the Treatment of Mild-Moderate Alzheimer's Disease.
Frölich L, Atri A, Ballard C, Tariot PN, Molinuevo JL, Boneva N, Geist MA, Raket LL, Cummings JL.
Frölich L, et al. Among authors: geist ma.
J Alzheimers Dis. 2019;67(1):303-313. doi: 10.3233/JAD-180595.
J Alzheimers Dis. 2019.
PMID: 30636738
Clinical Trial.
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Efficacy and safety of arimoclomol in Niemann-Pick disease type C: Results from a double-blind, randomised, placebo-controlled, multinational phase 2/3 trial of a novel treatment.
Mengel E, Patterson MC, Da Riol RM, Del Toro M, Deodato F, Gautschi M, Grunewald S, Grønborg S, Harmatz P, Héron B, Maier EM, Roubertie A, Santra S, Tylki-Szymanska A, Day S, Andreasen AK, Geist MA, Havnsøe Torp Petersen N, Ingemann L, Hansen T, Blaettler T, Kirkegaard T, Í Dali C.
Mengel E, et al. Among authors: geist ma.
J Inherit Metab Dis. 2021 Nov;44(6):1463-1480. doi: 10.1002/jimd.12428. Epub 2021 Sep 7.
J Inherit Metab Dis. 2021.
PMID: 34418116
Free PMC article.
Clinical Trial.
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Safety and efficacy of arimoclomol in patients with early amyotrophic lateral sclerosis (ORARIALS-01): a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial.
Benatar M, Hansen T, Rom D, Geist MA, Blaettler T, Camu W, Kuzma-Kozakiewicz M, van den Berg LH, Morales RJ, Chio A, Andersen PM, Pradat PF, Lange D, Van Damme P, Mora G, Grudniak M, Elliott M, Petri S, Olney N, Ladha S, Goyal NA, Meyer T, Hanna MG, Quinn C, Genge A, Zinman L, Jabari D, Shoesmith C, Ludolph AC, Neuwirth C, Nations S, Shefner JM, Turner MR, Wuu J, Bennett R, Dang H, Sundgreen C; ORARIALS-01 trial team.
Benatar M, et al. Among authors: geist ma.
Lancet Neurol. 2024 Jul;23(7):687-699. doi: 10.1016/S1474-4422(24)00134-0. Epub 2024 May 20.
Lancet Neurol. 2024.
PMID: 38782015
Clinical Trial.
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