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Small-molecule synergist of the Wnt/beta-catenin signaling pathway.
Zhang Q, Major MB, Takanashi S, Camp ND, Nishiya N, Peters EC, Ginsberg MH, Jian X, Randazzo PA, Schultz PG, Moon RT, Ding S. Zhang Q, et al. Among authors: nishiya n. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7444-8. doi: 10.1073/pnas.0702136104. Epub 2007 Apr 25. Proc Natl Acad Sci U S A. 2007. PMID: 17460038 Free PMC article.
CD98hc (SLC3A2) mediates integrin signaling.
Feral CC, Nishiya N, Fenczik CA, Stuhlmann H, Slepak M, Ginsberg MH. Feral CC, et al. Among authors: nishiya n. Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):355-60. doi: 10.1073/pnas.0404852102. Epub 2004 Dec 29. Proc Natl Acad Sci U S A. 2005. PMID: 15625115 Free PMC article.
Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.
Jones CA, London NR, Chen H, Park KW, Sauvaget D, Stockton RA, Wythe JD, Suh W, Larrieu-Lahargue F, Mukouyama YS, Lindblom P, Seth P, Frias A, Nishiya N, Ginsberg MH, Gerhardt H, Zhang K, Li DY. Jones CA, et al. Among authors: nishiya n. Nat Med. 2008 Apr;14(4):448-53. doi: 10.1038/nm1742. Epub 2008 Mar 16. Nat Med. 2008. PMID: 18345009 Free PMC article.
Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity.
Jones CA, Nishiya N, London NR, Zhu W, Sorensen LK, Chan AC, Lim CJ, Chen H, Zhang Q, Schultz PG, Hayallah AM, Thomas KR, Famulok M, Zhang K, Ginsberg MH, Li DY. Jones CA, et al. Among authors: nishiya n. Nat Cell Biol. 2009 Nov;11(11):1325-31. doi: 10.1038/ncb1976. Epub 2009 Oct 18. Nat Cell Biol. 2009. PMID: 19855388 Free PMC article.
IMU1003, an atrarate derivative, inhibits Wnt/β-catenin signaling.
Yonezawa H, Sugawara A, Sakyo T, Uehara Y, Kawano T, Nishiya N. Yonezawa H, et al. Among authors: nishiya n. Biochem Biophys Res Commun. 2020 Nov 12;532(3):440-445. doi: 10.1016/j.bbrc.2020.08.031. Epub 2020 Sep 3. Biochem Biophys Res Commun. 2020. PMID: 32891433
Clotrimazole inhibits the Wnt/β-catenin pathway by activating two eIF2α kinases: The heme-regulated translational inhibitor and the double-stranded RNA-induced protein kinase.
Yonezawa H, Ogawa M, Katayama S, Shimizu Y, Omori N, Oku Y, Sakyo T, Uehara Y, Nishiya N. Yonezawa H, et al. Among authors: nishiya n. Biochem Biophys Res Commun. 2018 Nov 17;506(1):183-188. doi: 10.1016/j.bbrc.2018.10.053. Epub 2018 Oct 17. Biochem Biophys Res Commun. 2018. PMID: 30342850
38 results