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The rate-limiting step in yeast PGK1 mRNA degradation is an endonucleolytic cleavage in the 3'-terminal part of the coding region.
Vreken P, Raué HA. Vreken P, et al. Mol Cell Biol. 1992 Jul;12(7):2986-96. doi: 10.1128/mcb.12.7.2986-2996.1992. Mol Cell Biol. 1992. PMID: 1320194 Free PMC article.
Insertion of an 18-nucleotide-long poly(G) tract into the 3'-terminal untranslated region of yeast phosphoglycerate kinase (PGK1) mRNA increases its chemical half-life by about a factor of 2 (P. Vreken, R. Van der Veen, V. C. H. F. de Regt, A. L. de Maat, R. J. Plan …
Insertion of an 18-nucleotide-long poly(G) tract into the 3'-terminal untranslated region of yeast phosphoglycerate kinase (PGK1) mRNA incre …
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