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Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis.
Chakravarthy MV, Zhu Y, López M, Yin L, Wozniak DF, Coleman T, Hu Z, Wolfgang M, Vidal-Puig A, Lane MD, Semenkovich CF. Chakravarthy MV, et al. Among authors: lopez m. J Clin Invest. 2007 Sep;117(9):2539-52. doi: 10.1172/JCI31183. J Clin Invest. 2007. PMID: 17694178 Free PMC article.
Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis.
Lelliott CJ, López M, Curtis RK, Parker N, Laudes M, Yeo G, Jimenez-Liñan M, Grosse J, Saha AK, Wiggins D, Hauton D, Brand MD, O'Rahilly S, Griffin JL, Gibbons GF, Vidal-Puig A. Lelliott CJ, et al. Among authors: lopez m. FASEB J. 2005 Jul;19(9):1108-19. doi: 10.1096/fj.04-3196com. FASEB J. 2005. PMID: 15985534
PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism.
Medina-Gomez G, Gray SL, Yetukuri L, Shimomura K, Virtue S, Campbell M, Curtis RK, Jimenez-Linan M, Blount M, Yeo GS, Lopez M, Seppänen-Laakso T, Ashcroft FM, Oresic M, Vidal-Puig A. Medina-Gomez G, et al. Among authors: lopez m. PLoS Genet. 2007 Apr 27;3(4):e64. doi: 10.1371/journal.pgen.0030064. PLoS Genet. 2007. PMID: 17465682 Free PMC article.
Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin.
López M, Lage R, Saha AK, Pérez-Tilve D, Vázquez MJ, Varela L, Sangiao-Alvarellos S, Tovar S, Raghay K, Rodríguez-Cuenca S, Deoliveira RM, Castañeda T, Datta R, Dong JZ, Culler M, Sleeman MW, Alvarez CV, Gallego R, Lelliott CJ, Carling D, Tschöp MH, Diéguez C, Vidal-Puig A. López M, et al. Cell Metab. 2008 May;7(5):389-99. doi: 10.1016/j.cmet.2008.03.006. Cell Metab. 2008. PMID: 18460330 Free article.
Brain lipogenesis and regulation of energy metabolism.
López M, Vidal-Puig A. López M, et al. Curr Opin Clin Nutr Metab Care. 2008 Jul;11(4):483-90. doi: 10.1097/MCO.0b013e328302f3d8. Curr Opin Clin Nutr Metab Care. 2008. PMID: 18542011 Review.
7,277 results