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Novel semi-synthetic glycopeptide antibiotics active against methicillin-resistant staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE): doubly-modified water-soluble derivatives of chloroorienticin B.
Yoshida O, Yasukata T, Sumino Y, Munekage T, Narukawa Y, Nishitani Y. Yoshida O, et al. Among authors: nishitani y. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3027-31. doi: 10.1016/s0960-894x(02)00664-9. Bioorg Med Chem Lett. 2002. PMID: 12372494
S-3578, a new broad spectrum parenteral cephalosporin exhibiting potent activity against both methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. Synthesis and structure-activity relationships.
Yoshizawa H, Itani H, Ishikura K, Irie T, Yokoo K, Kubota T, Minami K, Iwaki T, Miwa H, Nishitani Y. Yoshizawa H, et al. Among authors: nishitani y. J Antibiot (Tokyo). 2002 Nov;55(11):975-92. doi: 10.7164/antibiotics.55.975. J Antibiot (Tokyo). 2002. PMID: 12546419 Free article.
New broad-spectrum parenteral cephalosporins exhibiting potent activity against both methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. Part 2: Synthesis and structure-activity relationships in the S-3578 series.
Yoshizawa H, Kubota T, Itani H, Ishitobi H, Miwa H, Nishitani Y. Yoshizawa H, et al. Among authors: nishitani y. Bioorg Med Chem. 2004 Aug 1;12(15):4211-9. doi: 10.1016/j.bmc.2004.05.022. Bioorg Med Chem. 2004. PMID: 15246097
New broad-spectrum parenteral cephalosporins exhibiting potent activity against both methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. Part 3: 7beta-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-ethoxyiminoacetamido] cephalosporins bearing 4-[3-(aminoalkyl)-ureido]-1-pyridinium at C-3'.
Yoshizawa H, Kubota T, Itani H, Minami K, Miwa H, Nishitani Y. Yoshizawa H, et al. Among authors: nishitani y. Bioorg Med Chem. 2004 Aug 1;12(15):4221-31. doi: 10.1016/j.bmc.2004.05.021. Bioorg Med Chem. 2004. PMID: 15246098
A novel series of parenteral cephalosporins exhibiting potent activities against both Pseudomonas aeruginosa and other gram-negative pathogens. Part 2: Synthesis and structure-activity relationships.
Yamawaki K, Nomura T, Yasukata T, Tanimoto N, Uotani K, Miwa H, Yamano Y, Takeda K, Nishitani Y. Yamawaki K, et al. Among authors: nishitani y. Bioorg Med Chem. 2008 Feb 15;16(4):1632-47. doi: 10.1016/j.bmc.2007.11.028. Epub 2007 Nov 17. Bioorg Med Chem. 2008. PMID: 18065229
Cefiderocol (S-649266), A new siderophore cephalosporin exhibiting potent activities against Pseudomonas aeruginosa and other gram-negative pathogens including multi-drug resistant bacteria: Structure activity relationship.
Aoki T, Yoshizawa H, Yamawaki K, Yokoo K, Sato J, Hisakawa S, Hasegawa Y, Kusano H, Sano M, Sugimoto H, Nishitani Y, Sato T, Tsuji M, Nakamura R, Nishikawa T, Yamano Y. Aoki T, et al. Among authors: nishitani y. Eur J Med Chem. 2018 Jul 15;155:847-868. doi: 10.1016/j.ejmech.2018.06.014. Epub 2018 Jun 8. Eur J Med Chem. 2018. PMID: 29960205
219 results