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p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, DePinho RA. Zheng H, et al. Among authors: stommel jm. Nature. 2008 Oct 23;455(7216):1129-33. doi: 10.1038/nature07443. Nature. 2008. PMID: 18948956 Free PMC article.
Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma.
Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, dePinho RA. Zheng H, et al. Among authors: stommel jm. Cold Spring Harb Symp Quant Biol. 2008;73:427-37. doi: 10.1101/sqb.2008.73.047. Epub 2009 Jan 15. Cold Spring Harb Symp Quant Biol. 2008. PMID: 19150964
Mig-6 controls EGFR trafficking and suppresses gliomagenesis.
Ying H, Zheng H, Scott K, Wiedemeyer R, Yan H, Lim C, Huang J, Dhakal S, Ivanova E, Xiao Y, Zhang H, Hu J, Stommel JM, Lee MA, Chen AJ, Paik JH, Segatto O, Brennan C, Elferink LA, Wang YA, Chin L, DePinho RA. Ying H, et al. Among authors: stommel jm. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6912-7. doi: 10.1073/pnas.0914930107. Epub 2010 Mar 29. Proc Natl Acad Sci U S A. 2010. PMID: 20351267 Free PMC article.
Malignant astrocytic glioma: genetics, biology, and paths to treatment.
Furnari FB, Fenton T, Bachoo RM, Mukasa A, Stommel JM, Stegh A, Hahn WC, Ligon KL, Louis DN, Brennan C, Chin L, DePinho RA, Cavenee WK. Furnari FB, et al. Among authors: stommel jm. Genes Dev. 2007 Nov 1;21(21):2683-710. doi: 10.1101/gad.1596707. Genes Dev. 2007. PMID: 17974913 Free article. Review.
Pancreatic cancers require autophagy for tumor growth.
Yang S, Wang X, Contino G, Liesa M, Sahin E, Ying H, Bause A, Li Y, Stommel JM, Dell'antonio G, Mautner J, Tonon G, Haigis M, Shirihai OS, Doglioni C, Bardeesy N, Kimmelman AC. Yang S, et al. Among authors: stommel jm. Genes Dev. 2011 Apr 1;25(7):717-29. doi: 10.1101/gad.2016111. Epub 2011 Mar 15. Genes Dev. 2011. PMID: 21406549 Free PMC article.
Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy.
Nitta M, Kozono D, Kennedy R, Stommel J, Ng K, Zinn PO, Kushwaha D, Kesari S, Inda MM, Wykosky J, Furnari F, Hoadley KA, Chin L, DePinho RA, Cavenee WK, D'Andrea A, Chen CC. Nitta M, et al. PLoS One. 2010 May 24;5(5):e10767. doi: 10.1371/journal.pone.0010767. PLoS One. 2010. PMID: 20532243 Free PMC article.
Exploiting Radiation-Induced Signaling to Increase the Susceptibility of Resistant Cancer Cells to Targeted Drugs: AKT and mTOR Inhibitors as an Example.
Eke I, Makinde AY, Aryankalayil MJ, Sandfort V, Palayoor ST, Rath BH, Liotta L, Pierobon M, Petricoin EF, Brown MF, Stommel JM, Ahmed MM, Coleman CN. Eke I, et al. Among authors: stommel jm. Mol Cancer Ther. 2018 Feb;17(2):355-367. doi: 10.1158/1535-7163.MCT-17-0262. Epub 2017 Aug 11. Mol Cancer Ther. 2018. PMID: 28802252 Free PMC article.
23 results