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Ras guanine nucleotide-releasing protein 4 is aberrantly expressed in the fibroblast-like synoviocytes of patients with rheumatoid arthritis and controls their proliferation.
Kono M, Yasuda S, Stevens RL, Koide H, Kurita T, Shimizu Y, Kanetsuka Y, Oku K, Bohgaki T, Amengual O, Horita T, Shimizu T, Majima T, Koike T, Atsumi T. Kono M, et al. Among authors: stevens rl. Arthritis Rheumatol. 2015 Feb;67(2):396-407. doi: 10.1002/art.38924. Arthritis Rheumatol. 2015. PMID: 25330932
Mast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscle.
Abonia JP, Friend DS, Austen WG Jr, Moore FD Jr, Carroll MC, Chan R, Afnan J, Humbles A, Gerard C, Knight P, Kanaoka Y, Yasuda S, Morokawa N, Austen KF, Stevens RL, Gurish MF. Abonia JP, et al. Among authors: stevens rl. J Immunol. 2005 Jun 1;174(11):7285-91. doi: 10.4049/jimmunol.174.11.7285. J Immunol. 2005. PMID: 15905575 Free PMC article.
Mouse mast cells express the tryptic protease neuropsin/Prss19.
Wong GW, Yang Y, Yasuda S, Li L, Stevens RL. Wong GW, et al. Among authors: stevens rl. Biochem Biophys Res Commun. 2003 Mar 28;303(1):320-5. doi: 10.1016/s0006-291x(03)00339-5. Biochem Biophys Res Commun. 2003. PMID: 12646205
The Diacylglycerol-dependent translocation of ras guanine nucleotide-releasing protein 4 inside a human mast cell line results in substantial phenotypic changes, including expression of interleukin 13 receptor alpha2.
Katsoulotos GP, Qi M, Qi JC, Tanaka K, Hughes WE, Molloy TJ, Adachi R, Stevens RL, Krilis SA. Katsoulotos GP, et al. Among authors: stevens rl. J Biol Chem. 2008 Jan 18;283(3):1610-1621. doi: 10.1074/jbc.M707042200. Epub 2007 Nov 16. J Biol Chem. 2008. PMID: 18024961 Free article.
Biochemical and functional characterization of human transmembrane tryptase (TMT)/tryptase gamma. TMT is an exocytosed mast cell protease that induces airway hyperresponsiveness in vivo via an interleukin-13/interleukin-4 receptor alpha/signal transducer and activator of transcription (STAT) 6-dependent pathway.
Wong GW, Foster PS, Yasuda S, Qi JC, Mahalingam S, Mellor EA, Katsoulotos G, Li L, Boyce JA, Krilis SA, Stevens RL. Wong GW, et al. Among authors: stevens rl. J Biol Chem. 2002 Nov 1;277(44):41906-15. doi: 10.1074/jbc.M205868200. Epub 2002 Aug 22. J Biol Chem. 2002. PMID: 12194977 Free article.
RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and demonstration of the importance of RasGRP4 in mast cell development and function.
Yang Y, Li L, Wong GW, Krilis SA, Madhusudhan MS, Sali A, Stevens RL. Yang Y, et al. Among authors: stevens rl. J Biol Chem. 2002 Jul 12;277(28):25756-74. doi: 10.1074/jbc.M202575200. Epub 2002 Apr 15. J Biol Chem. 2002. PMID: 11956218 Free article.
282 results