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Estrogen receptor dependent inhibitors of NF-kappaB transcriptional activation-1 synthesis and biological evaluation of substituted 2-cyanopropanoic acid derivatives: pathway selective inhibitors of NF-kappaB, a potential treatment for rheumatoid arthritis.
Caggiano TJ, Brazzale A, Ho DM, Kraml CM, Trybulski E, Chadwick CC, Chippari S, Borges-Marcucci L, Eckert A, Keith JC, Kenney T, Harnish DC. Caggiano TJ, et al. Among authors: ho dm. J Med Chem. 2007 Nov 1;50(22):5245-8. doi: 10.1021/jm701013k. Epub 2007 Sep 29. J Med Chem. 2007. PMID: 17902637
Selective Kv1.5 blockers: development of (R)-1-(methylsulfonylamino)-3-[2-(4-methoxyphenyl)ethyl]-4-(4-methoxyphenyl)-2-imidazolidinone (KVI-020/WYE-160020) as a potential treatment for atrial arrhythmia.
Blass BE, Fensome A, Trybulski E, Magolda R, Gardell SJ, Liu K, Samuel M, Feingold I, Huselton C, Jackson CM, Djandjighian L, Ho D, Hennan J, Janusz JM. Blass BE, et al. J Med Chem. 2009 Nov 12;52(21):6531-4. doi: 10.1021/jm901042m. J Med Chem. 2009. PMID: 19888755
Heterocyclic cycloalkanol ethylamines as norepinephrine reuptake inhibitors.
Sabatucci JP, Mahaney PE, Leiter J, Johnston G, Burroughs K, Cosmi S, Zhang Y, Ho D, Deecher DC, Trybulski E. Sabatucci JP, et al. Bioorg Med Chem Lett. 2010 May 1;20(9):2809-12. doi: 10.1016/j.bmcl.2010.03.059. Epub 2010 Mar 15. Bioorg Med Chem Lett. 2010. PMID: 20378347
Structure-activity relationships of the cycloalkanol ethylamine scaffold: discovery of selective norepinephrine reuptake inhibitors.
Mahaney PE, Gavrin LK, Trybulski EJ, Stack GP, Vu TA, Cohn ST, Ye F, Belardi JK, Santilli AA, Sabatucci JP, Leiter J, Johnston GH, Bray JA, Burroughs KD, Cosmi SA, Leventhal L, Koury EJ, Zhang Y, Mugford CA, Ho DM, Rosenzweig-Lipson SJ, Platt B, Smith VA, Deecher DC. Mahaney PE, et al. Among authors: ho dm. J Med Chem. 2008 Jul 10;51(13):4038-49. doi: 10.1021/jm8002262. Epub 2008 Jun 17. J Med Chem. 2008. PMID: 18557608
A pentacene with a 144 degrees twist.
Lu J, Ho DM, Vogelaar NJ, Kraml CM, Pascal RA Jr. Lu J, et al. Among authors: ho dm. J Am Chem Soc. 2004 Sep 15;126(36):11168-9. doi: 10.1021/ja046576w. J Am Chem Soc. 2004. PMID: 15355095
Thermal C1-C5 diradical cyclization of enediynes.
Vavilala C, Byrne N, Kraml CM, Ho DM, Pascal RA Jr. Vavilala C, et al. Among authors: ho dm. J Am Chem Soc. 2008 Oct 15;130(41):13549-51. doi: 10.1021/ja803413f. Epub 2008 Sep 18. J Am Chem Soc. 2008. PMID: 18798628
221 results