Scammells PJ - Search Results

1

Structure-activity relationships of adenosines with heterocyclic N6-substituents.

Ashton TD, Aumann KM, Baker SP, Schiesser CH, Scammells PJ. Ashton TD, et al. Among authors: scammells pj. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6779-84. doi: 10.1016/j.bmcl.2007.10.028. Epub 2007 Oct 17. Bioorg Med Chem Lett. 2007. PMID: 17967536

2

Substituted 1,3-dipropylxanthines as irreversible antagonists of A1 adenosine receptors.

Scammells PJ, Baker SP, Belardinelli L, Olsson RA. Scammells PJ, et al. J Med Chem. 1994 Aug 19;37(17):2704-12. doi: 10.1021/jm00043a010. J Med Chem. 1994. PMID: 8064798

3

1,3-Dipropyl-8-[2-(5,6-epoxy)norbornyl]xanthine, a potent, specific and selective A1 adenosine receptor antagonist in the guinea pig heart and brain and in DDT1MF-2 cells.

Belardinelli L, Shryock JC, Zhang Y, Scammells PJ, Olsson R, Dennis D, Milner P, Pfister J, Baker SP. Belardinelli L, et al. Among authors: scammells pj. J Pharmacol Exp Ther. 1995 Dec;275(3):1167-76. J Pharmacol Exp Ther. 1995. PMID: 8531078

4

A novel irreversible antagonist of the A1-adenosine receptor.

Srinivas M, Shryock JC, Scammells PJ, Ruble J, Baker SP, Belardinelli L. Srinivas M, et al. Among authors: scammells pj. Mol Pharmacol. 1996 Jul;50(1):196-205. Mol Pharmacol. 1996. PMID: 8700113

5

XH-14 analogues as adenosine antagonists.

Scammells PJ, Baker SP, Beauglehole AR. Scammells PJ, et al. Bioorg Med Chem. 1998 Sep;6(9):1517-24. doi: 10.1016/s0968-0896(98)00093-5. Bioorg Med Chem. 1998. PMID: 9801823

6

N6-(5,6-epoxynorbornyl)adenosine analogs as A1 adenosine agonists.

Wright DM, Baker SP, Stewart SG, Scammells PJ. Wright DM, et al. Among authors: scammells pj. Bioorg Med Chem Lett. 1998 Dec 15;8(24):3647-8. doi: 10.1016/s0960-894x(98)00668-4. Bioorg Med Chem Lett. 1998. PMID: 9934487

7

Adenosine receptor ligands with oxygenated N6-substituents.

Hutchinson SA, Baker SP, Scammells PJ. Hutchinson SA, et al. Among authors: scammells pj. Bioorg Med Chem Lett. 1999 Apr 5;9(7):933-6. doi: 10.1016/s0960-894x(99)00109-2. Bioorg Med Chem Lett. 1999. PMID: 10230614

8

Differential A(1)-adenosine receptor reserve for inhibition of cyclic AMP accumulation and G-protein activation in DDT(1) MF-2 cells.

Baker SP, Scammells PJ, Belardinelli L. Baker SP, et al. Among authors: scammells pj. Br J Pharmacol. 2000 Jul;130(5):1156-64. doi: 10.1038/sj.bjp.0703405. Br J Pharmacol. 2000. PMID: 10882402 Free PMC article.

9

Fluorosulfonyl-substituted xanthines as selective irreversible antagonists for the A(1)-adenosine receptor.

Beauglehole AR, Baker SP, Scammells PJ. Beauglehole AR, et al. Among authors: scammells pj. J Med Chem. 2000 Dec 28;43(26):4973-80. doi: 10.1021/jm000181f. J Med Chem. 2000. PMID: 11150167

10

New 2,N6-disubstituted adenosines: potent and selective A1 adenosine receptor agonists.

Hutchinson SA, Baker SP, Scammells PJ. Hutchinson SA, et al. Among authors: scammells pj. Bioorg Med Chem. 2002 Apr;10(4):1115-22. doi: 10.1016/s0968-0896(01)00384-4. Bioorg Med Chem. 2002. PMID: 11836122

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