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BRD-810 is a highly selective MCL1 inhibitor with optimized in vivo clearance and robust efficacy in solid and hematological tumor models.
Rauh U, Wei G, Serrano-Wu M, Kosmidis G, Kaulfuss S, Siegel F, Thede K, McFarland J, Lemke CT, Werbeck N, Nowak-Reppel K, Pilari S, Menz S, Ocker M, Zhang W, Davis K, Poncet-Montange G, Roth J, Daniels D, Kaushik VK, Hubbard B, Ziegelbauer K, Golub TR. Rauh U, et al. Among authors: mcfarland j. Nat Cancer. 2024 Aug 23. doi: 10.1038/s43018-024-00814-0. Online ahead of print. Nat Cancer. 2024. PMID: 39179926
Germline variation contributes to false negatives in CRISPR-based experiments with varying burden across ancestries.
Misek SA, Fultineer A, Kalfon J, Noorbakhsh J, Boyle I, Roy P, Dempster J, Petronio L, Huang K, Saadat A, Green T, Brown A, Doench JG, Root DE, McFarland JM, Beroukhim R, Boehm JS. Misek SA, et al. Among authors: mcfarland jm. Nat Commun. 2024 Jun 7;15(1):4892. doi: 10.1038/s41467-024-48957-z. Nat Commun. 2024. PMID: 38849329 Free PMC article.
Comparison of EEP and TURP long-term outcomes: systematic review and meta-analysis.
Morozov A, Taratkin M, Shpikina A, Ehrlich Y, McFarland J, Dymov A, Kozlov V, Fajkovic H, Rivas JG, Lusuardi L, Teoh JY, Herrmann T, Baniel J, Enikeev D. Morozov A, et al. Among authors: mcfarland j. World J Urol. 2023 Dec;41(12):3471-3483. doi: 10.1007/s00345-023-04666-8. Epub 2023 Nov 18. World J Urol. 2023. PMID: 37980297 Review.
The path to 1.5 °C requires ratcheting of climate pledges.
Iyer G, Ou Y, Edmonds J, Fawcett AA, Hultman N, McFarland J, Fuhrman J, Waldhoff S, McJeon H. Iyer G, et al. Among authors: mcfarland j. Nat Clim Chang. 2022 Nov 10;12:1092-1093. doi: 10.1038/s41558-022-01517-z. Nat Clim Chang. 2022. PMID: 37829843 Free PMC article. No abstract available.
Ratcheting of climate pledges needed to limit peak global warming.
Iyer G, Ou Y, Edmonds J, Fawcett AA, Hultman N, McFarland J, Fuhrman J, Waldhoff S, McJeon H. Iyer G, et al. Among authors: mcfarland j. Nat Clim Chang. 2022 Nov 10;12:1129-1135. doi: 10.1038/s41558-022-01508-0. Nat Clim Chang. 2022. PMID: 37829842 Free PMC article.
538 results