Dole K - Search Results

1

Vildagliptin, a novel dipeptidyl peptidase IV inhibitor, has no pharmacokinetic interactions with the antihypertensive agents amlodipine, valsartan, and ramipril in healthy subjects.

He YL, Ligueros-Saylan M, Sunkara G, Sabo R, Zhao C, Wang Y, Campestrini J, Pommier F, Dole K, Marion A, Dole WP, Howard D. He YL, et al. Among authors: dole k, dole wp. J Clin Pharmacol. 2008 Jan;48(1):85-95. doi: 10.1177/0091270007307880. Epub 2007 Nov 6. J Clin Pharmacol. 2008. PMID: 17986525 Clinical Trial.

2

Evaluation of the potential for steady-state pharmacokinetic interaction between vildagliptin and simvastatin in healthy subjects.

Ayalasomayajula SP, Dole K, He YL, Ligueros-Saylan M, Wang Y, Campestrini J, Humbert H, Sunkara G. Ayalasomayajula SP, et al. Among authors: dole k. Curr Med Res Opin. 2007 Dec;23(12):2913-20. doi: 10.1185/030079907X233296. Curr Med Res Opin. 2007. PMID: 17931461 Clinical Trial.

3

Ketoconazole increases fingolimod blood levels in a drug interaction via CYP4F2 inhibition.

Kovarik JM, Dole K, Riviere GJ, Pommier F, Maton S, Jin Y, Lasseter KC, Schmouder RL. Kovarik JM, et al. Among authors: dole k. J Clin Pharmacol. 2009 Feb;49(2):212-8. doi: 10.1177/0091270008329553. Epub 2008 Dec 31. J Clin Pharmacol. 2009. PMID: 19118083 Clinical Trial.

4

The effects of CYP3A4 induction and inhibition on the pharmacokinetics of alisporivir in humans.

Barve A, Kovacs SJ, Ke J, Crabbe R, Grosgurin P, Menetrey A, Nicolas-Métral V, Dabovic K, Dole K, Zhang J, Praestgaard J, Sunkara G, Stein D. Barve A, et al. Among authors: dole k. Clin Pharmacol Drug Dev. 2015 Jan;4(1):25-32. doi: 10.1002/cpdd.114. Epub 2014 May 26. Clin Pharmacol Drug Dev. 2015. PMID: 27128001 Clinical Trial.

5

Sex differences in cyclosporine pharmacokinetics and ABCB1 gene expression in mononuclear blood cells in African American and Caucasian renal transplant recipients.

Tornatore KM, Brazeau D, Dole K, Danison R, Wilding G, Leca N, Gundroo A, Gillis K, Zack J, DiFrancesco R, Venuto RC. Tornatore KM, et al. Among authors: dole k. J Clin Pharmacol. 2013 Oct;53(10):1039-47. doi: 10.1002/jcph.123. Epub 2013 Jul 3. J Clin Pharmacol. 2013. PMID: 23908147

6

Mycophenolic acid pharmacokinetics during maintenance immunosuppression in African American and Caucasian renal transplant recipients.

Tornatore KM, Sudchada P, Dole K, DiFrancesco R, Leca N, Gundroo AC, Danison RT, Attwood K, Wilding GE, Zack J, Forrest A, Venuto RC. Tornatore KM, et al. Among authors: dole k. J Clin Pharmacol. 2011 Aug;51(8):1213-22. doi: 10.1177/0091270010382909. Epub 2011 Jan 5. J Clin Pharmacol. 2011. PMID: 21209244 Clinical Trial.

7

Clinical disposition, metabolism and in vitro drug-drug interaction properties of omadacycline.

Flarakos J, Du Y, Gu H, Wang L, Einolf HJ, Chun DY, Zhu B, Alexander N, Natrillo A, Hanna I, Ting L, Zhou W, Dole K, Sun H, Kovacs SJ, Stein DS, Tanaka SK, Villano S, Mangold JB. Flarakos J, et al. Among authors: dole k. Xenobiotica. 2017 Aug;47(8):682-696. doi: 10.1080/00498254.2016.1213465. Epub 2016 Aug 8. Xenobiotica. 2017. PMID: 27499331

8

A Diacylglycerol Transferase 1 Inhibitor Is a Potent Hepatitis C Antiviral in Vitro but Not in Patients in a Randomized Clinical Trial.

Gane E, Stedman C, Dole K, Chen J, Meyers CD, Wiedmann B, Zhang J, Raman P, Colvin RA. Gane E, et al. Among authors: dole k. ACS Infect Dis. 2017 Feb 10;3(2):144-151. doi: 10.1021/acsinfecdis.6b00138. Epub 2016 Nov 8. ACS Infect Dis. 2017. PMID: 27788579 Clinical Trial.

9

A First-in-Human Study To Assess the Safety and Pharmacokinetics of Monoclonal Antibodies against Human Cytomegalovirus in Healthy Volunteers.

Dole K, Segal FP, Feire A, Magnusson B, Rondon JC, Vemula J, Yu J, Pang Y, Pertel P. Dole K, et al. Antimicrob Agents Chemother. 2016 Apr 22;60(5):2881-7. doi: 10.1128/AAC.02698-15. Print 2016 May. Antimicrob Agents Chemother. 2016. PMID: 26926639 Free PMC article. Clinical Trial.

10

Detection of cytochrome P450 and other drug-metabolizing enzyme mRNAs in peripheral blood mononuclear cells using DNA arrays.

Nguyen LT, Ramanathan M, Weinstock-Guttman B, Dole K, Miller C, Planter M, Patrick K, Brownscheidle C, Jacobs LD. Nguyen LT, et al. Among authors: dole k. Drug Metab Dispos. 2000 Aug;28(8):987-93. Drug Metab Dispos. 2000. PMID: 10901711

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