Pickett C - Search Results

1

Posaconazole (Noxafil, SCH 56592), a new azole antifungal drug, was a discovery based on the isolation and mass spectral characterization of a circulating metabolite of an earlier lead (SCH 51048).

Nomeir AA, Pramanik BN, Heimark L, Bennett F, Veals J, Bartner P, Hilbert M, Saksena A, McNamara P, Girijavallabhan V, Ganguly AK, Lovey R, Pike R, Wang H, Liu YT, Kumari P, Korfmacher W, Lin CC, Cacciapuoti A, Loebenberg D, Hare R, Miller G, Pickett C. Nomeir AA, et al. Among authors: pickett c. J Mass Spectrom. 2008 Apr;43(4):509-17. doi: 10.1002/jms.1341. J Mass Spectrom. 2008. PMID: 18059003

2

Role of protein phosphorylation in the regulation of NF-E2-related factor 2 activity.

Sherratt PJ, Huang HC, Nguyen T, Pickett CB. Sherratt PJ, et al. Among authors: pickett cb. Methods Enzymol. 2004;378:286-301. doi: 10.1016/S0076-6879(04)78022-2. Methods Enzymol. 2004. PMID: 15038976 Review. No abstract available.

3

The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress.

Nguyen T, Yang CS, Pickett CB. Nguyen T, et al. Free Radic Biol Med. 2004 Aug 15;37(4):433-41. doi: 10.1016/j.freeradbiomed.2004.04.033. Free Radic Biol Med. 2004. PMID: 15256215 Review.

4

The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation.

Nioi P, Nguyen T, Sherratt PJ, Pickett CB. Nioi P, et al. Mol Cell Biol. 2005 Dec;25(24):10895-906. doi: 10.1128/MCB.25.24.10895-10906.2005. Mol Cell Biol. 2005. PMID: 16314513 Free PMC article.

5

Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1.

Nguyen T, Sherratt PJ, Nioi P, Yang CS, Pickett CB. Nguyen T, et al. J Biol Chem. 2005 Sep 16;280(37):32485-92. doi: 10.1074/jbc.M503074200. Epub 2005 Jul 6. J Biol Chem. 2005. PMID: 16000310 Free article.

6

Impact of health care reform on research innovativeness.

Pickett C. Pickett C. Ann N Y Acad Sci. 1994 Nov 4;729:106-10; discussion 139-42. doi: 10.1111/j.1749-6632.1994.tb12220.x. Ann N Y Acad Sci. 1994. PMID: 7998721 No abstract available.

7

Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway.

Mirza A, McGuirk M, Hockenberry TN, Wu Q, Ashar H, Black S, Wen SF, Wang L, Kirschmeier P, Bishop WR, Nielsen LL, Pickett CB, Liu S. Mirza A, et al. Oncogene. 2002 Apr 18;21(17):2613-22. doi: 10.1038/sj.onc.1205353. Oncogene. 2002. PMID: 11965534

8

Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2.

Huang HC, Nguyen T, Pickett CB. Huang HC, et al. Among authors: pickett cb. Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12475-80. doi: 10.1073/pnas.220418997. Proc Natl Acad Sci U S A. 2000. PMID: 11035812 Free PMC article.

9

Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription.

Huang HC, Nguyen T, Pickett CB. Huang HC, et al. Among authors: pickett cb. J Biol Chem. 2002 Nov 8;277(45):42769-74. doi: 10.1074/jbc.M206911200. Epub 2002 Aug 26. J Biol Chem. 2002. PMID: 12198130 Free article.

10

Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome.

Nguyen T, Sherratt PJ, Huang HC, Yang CS, Pickett CB. Nguyen T, et al. Among authors: pickett cb. J Biol Chem. 2003 Feb 14;278(7):4536-41. doi: 10.1074/jbc.M207293200. Epub 2002 Nov 22. J Biol Chem. 2003. PMID: 12446695 Free article.

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