Brown JR - Search Results

1

Glycan antagonists and inhibitors: a fount for drug discovery.

Brown JR, Crawford BE, Esko JD. Brown JR, et al. Crit Rev Biochem Mol Biol. 2007 Nov-Dec;42(6):481-515. doi: 10.1080/10409230701751611. Crit Rev Biochem Mol Biol. 2007. PMID: 18066955 Review.

2

Expression patterns of alpha 2,3-sialyltransferases and alpha 1,3-fucosyltransferases determine the mode of sialyl Lewis X inhibition by disaccharide decoys.

Brown JR, Fuster MM, Whisenant T, Esko JD. Brown JR, et al. J Biol Chem. 2003 Jun 27;278(26):23352-9. doi: 10.1074/jbc.M303093200. Epub 2003 Apr 9. J Biol Chem. 2003. PMID: 12686549 Free article.

3

Synthesis and biological evaluation of gem-diamine 1-N-iminosugars related to L-iduronic acid as inhibitors of heparan sulfate 2-O-sulfotransferase.

Brown JR, Nishimura Y, Esko JD. Brown JR, et al. Bioorg Med Chem Lett. 2006 Feb;16(3):532-6. doi: 10.1016/j.bmcl.2005.10.055. Epub 2005 Nov 4. Bioorg Med Chem Lett. 2006. PMID: 16275065

4

Surfen, a small molecule antagonist of heparan sulfate.

Schuksz M, Fuster MM, Brown JR, Crawford BE, Ditto DP, Lawrence R, Glass CA, Wang L, Tor Y, Esko JD. Schuksz M, et al. Among authors: brown jr. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13075-80. doi: 10.1073/pnas.0805862105. Epub 2008 Aug 25. Proc Natl Acad Sci U S A. 2008. PMID: 18725627 Free PMC article.

5

Deoxygenated disaccharide analogs as specific inhibitors of beta1-4-galactosyltransferase 1 and selectin-mediated tumor metastasis.

Brown JR, Yang F, Sinha A, Ramakrishnan B, Tor Y, Qasba PK, Esko JD. Brown JR, et al. J Biol Chem. 2009 Feb 20;284(8):4952-9. doi: 10.1074/jbc.M805782200. Epub 2008 Dec 23. J Biol Chem. 2009. PMID: 19106107 Free PMC article.

6

WITHDRAWN: Glycan-based biomarkers for mucopolysaccharidoses.

Lawrence R, Brown JR, Lorey F, Dickson PI, Crawford BE, Esko JD. Lawrence R, et al. Among authors: brown jr. Dis Markers. 2013 Feb 8. doi: 10.3233/DMA-130970. Online ahead of print. Dis Markers. 2013. PMID: 23396297

7

Glycan-based biomarkers for mucopolysaccharidoses.

Lawrence R, Brown JR, Lorey F, Dickson PI, Crawford BE, Esko JD. Lawrence R, et al. Among authors: brown jr. Mol Genet Metab. 2014 Feb;111(2):73-83. doi: 10.1016/j.ymgme.2013.07.016. Epub 2013 Jul 29. Mol Genet Metab. 2014. PMID: 23958290 Free PMC article. Review.

8

Synthesis and glycan priming activity of acetylated disaccharides.

Sarkar AK, Brown JR, Esko JD. Sarkar AK, et al. Among authors: brown jr. Carbohydr Res. 2000 Nov 3;329(2):287-300. doi: 10.1016/s0008-6215(00)00200-7. Carbohydr Res. 2000. PMID: 11117312

9

Biosynthesis of the linkage region of glycosaminoglycans: cloning and activity of galactosyltransferase II, the sixth member of the beta 1,3-galactosyltransferase family (beta 3GalT6).

Bai X, Zhou D, Brown JR, Crawford BE, Hennet T, Esko JD. Bai X, et al. Among authors: brown jr. J Biol Chem. 2001 Dec 21;276(51):48189-95. doi: 10.1074/jbc.M107339200. Epub 2001 Sep 10. J Biol Chem. 2001. PMID: 11551958 Free article.

10

Heparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins.

Wang L, Brown JR, Varki A, Esko JD. Wang L, et al. Among authors: brown jr. J Clin Invest. 2002 Jul;110(1):127-36. doi: 10.1172/JCI14996. J Clin Invest. 2002. PMID: 12093896 Free PMC article.

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