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The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells.
Melillo RM, Castellone MD, Guarino V, De Falco V, Cirafici AM, Salvatore G, Caiazzo F, Basolo F, Giannini R, Kruhoffer M, Orntoft T, Fusco A, Santoro M. Melillo RM, et al. Among authors: de falco v. J Clin Invest. 2005 Apr;115(4):1068-81. doi: 10.1172/JCI22758. Epub 2005 Mar 10. J Clin Invest. 2005. PMID: 15761501 Free PMC article. Retracted.
BRAF is a therapeutic target in aggressive thyroid carcinoma.
Salvatore G, De Falco V, Salerno P, Nappi TC, Pepe S, Troncone G, Carlomagno F, Melillo RM, Wilhelm SM, Santoro M. Salvatore G, et al. Among authors: de falco v. Clin Cancer Res. 2006 Mar 1;12(5):1623-9. doi: 10.1158/1078-0432.CCR-05-2378. Clin Cancer Res. 2006. PMID: 16533790 Free article.
86 results