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The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy.
Mocanu MM, Nissen A, Eckermann K, Khlistunova I, Biernat J, Drexler D, Petrova O, Schönig K, Bujard H, Mandelkow E, Zhou L, Rune G, Mandelkow EM. Mocanu MM, et al. Among authors: eckermann k. J Neurosci. 2008 Jan 16;28(3):737-48. doi: 10.1523/JNEUROSCI.2824-07.2008. J Neurosci. 2008. PMID: 18199773 Free PMC article.
Fasudil attenuates aggregation of α-synuclein in models of Parkinson's disease.
Tatenhorst L, Eckermann K, Dambeck V, Fonseca-Ornelas L, Walle H, Lopes da Fonseca T, Koch JC, Becker S, Tönges L, Bähr M, Outeiro TF, Zweckstetter M, Lingor P. Tatenhorst L, et al. Among authors: eckermann k. Acta Neuropathol Commun. 2016 Apr 22;4:39. doi: 10.1186/s40478-016-0310-y. Acta Neuropathol Commun. 2016. PMID: 27101974 Free PMC article.
LRRK2 Promotes Tau Accumulation, Aggregation and Release.
Guerreiro PS, Gerhardt E, Lopes da Fonseca T, Bähr M, Outeiro TF, Eckermann K. Guerreiro PS, et al. Among authors: eckermann k. Mol Neurobiol. 2016 Jul;53(5):3124-3135. doi: 10.1007/s12035-015-9209-z. Epub 2015 May 27. Mol Neurobiol. 2016. PMID: 26014385
Protein phosphorylation in neurodegeneration: friend or foe?
Tenreiro S, Eckermann K, Outeiro TF. Tenreiro S, et al. Among authors: eckermann k. Front Mol Neurosci. 2014 May 13;7:42. doi: 10.3389/fnmol.2014.00042. eCollection 2014. Front Mol Neurosci. 2014. PMID: 24860424 Free PMC article. Review.
Mutant SOD1 detoxification mechanisms in intact single cells.
Ganesan S, Rohde G, Eckermann K, Sroka K, Schaefer MK, Dohm CP, Kermer P, Haase G, Wouters F, Bähr M, Weishaupt JH. Ganesan S, et al. Among authors: eckermann k. Cell Death Differ. 2008 Feb;15(2):312-21. doi: 10.1038/sj.cdd.4402262. Epub 2007 Nov 9. Cell Death Differ. 2008. PMID: 17992192
Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation.
Kunadt M, Eckermann K, Stuendl A, Gong J, Russo B, Strauss K, Rai S, Kügler S, Falomir Lockhart L, Schwalbe M, Krumova P, Oliveira LM, Bähr M, Möbius W, Levin J, Giese A, Kruse N, Mollenhauer B, Geiss-Friedlander R, Ludolph AC, Freischmidt A, Feiler MS, Danzer KM, Zweckstetter M, Jovin TM, Simons M, Weishaupt JH, Schneider A. Kunadt M, et al. Among authors: eckermann k. Acta Neuropathol. 2015 May;129(5):695-713. doi: 10.1007/s00401-015-1408-1. Epub 2015 Mar 17. Acta Neuropathol. 2015. PMID: 25778619 Free PMC article.
SUMO and Parkinson's disease.
Eckermann K. Eckermann K. Neuromolecular Med. 2013 Dec;15(4):737-59. doi: 10.1007/s12017-013-8259-5. Epub 2013 Aug 25. Neuromolecular Med. 2013. PMID: 23979994 Review.
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