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Dual mechanisms for the fibrate-mediated repression of proprotein convertase subtilisin/kexin type 9.
J Biol Chem. 2008 Apr 11;283(15):9666-73. doi: 10.1074/jbc.M705831200. Epub 2008 Feb 3.
J Biol Chem. 2008.
PMID: 18245819
Free article.
Cellular and secreted pro-protein convertase subtilisin/kexin type 9 catalytic activity in hepatocytes.
Kourimate S, Chétiveaux M, Jarnoux AL, Lalanne F, Costet P.
Kourimate S, et al. Among authors: jarnoux al.
Atherosclerosis. 2009 Sep;206(1):134-40. doi: 10.1016/j.atherosclerosis.2009.02.012. Epub 2009 Feb 20.
Atherosclerosis. 2009.
PMID: 19269636
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Hepatic PCSK9 expression is regulated by nutritional status via insulin and sterol regulatory element-binding protein 1c.
Costet P, Cariou B, Lambert G, Lalanne F, Lardeux B, Jarnoux AL, Grefhorst A, Staels B, Krempf M.
Costet P, et al. Among authors: jarnoux al.
J Biol Chem. 2006 Mar 10;281(10):6211-8. doi: 10.1074/jbc.M508582200. Epub 2006 Jan 6.
J Biol Chem. 2006.
PMID: 16407292
Free article.
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Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cells.
Lalanne F, Lambert G, Amar MJ, Chétiveaux M, Zaïr Y, Jarnoux AL, Ouguerram K, Friburg J, Seidah NG, Brewer HB Jr, Krempf M, Costet P.
Lalanne F, et al. Among authors: jarnoux al.
J Lipid Res. 2005 Jun;46(6):1312-9. doi: 10.1194/jlr.M400396-JLR200. Epub 2005 Mar 1.
J Lipid Res. 2005.
PMID: 15741654
Free article.
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Fasting induces hyperlipidemia in mice overexpressing proprotein convertase subtilisin kexin type 9: lack of modulation of very-low-density lipoprotein hepatic output by the low-density lipoprotein receptor.
Lambert G, Jarnoux AL, Pineau T, Pape O, Chetiveaux M, Laboisse C, Krempf M, Costet P.
Lambert G, et al. Among authors: jarnoux al.
Endocrinology. 2006 Oct;147(10):4985-95. doi: 10.1210/en.2006-0098. Epub 2006 Jun 22.
Endocrinology. 2006.
PMID: 16794006
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